Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003
We analyzed the effectiveness of personal protective equipment and oseltamivir use during the 2003 avian influenza A (H7N7) epidemic in the Netherlands by linking databases containing information about farm visits, human infections, and use of oseltamivir and personal protective equipment. Using a s...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2010-10-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/16/10/09-1412_article |
| _version_ | 1818275272300953600 |
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| author | Dennis E. te Beest Michiel van Boven Marian E.H. Bos Arjan Stegeman Marion P.G. Koopmans |
| author_facet | Dennis E. te Beest Michiel van Boven Marian E.H. Bos Arjan Stegeman Marion P.G. Koopmans |
| author_sort | Dennis E. te Beest |
| collection | DOAJ |
| description | We analyzed the effectiveness of personal protective equipment and oseltamivir use during the 2003 avian influenza A (H7N7) epidemic in the Netherlands by linking databases containing information about farm visits, human infections, and use of oseltamivir and personal protective equipment. Using a stringent case definition, based on self-reported conjunctivitis combined with a positive hemagglutination-inhibition assay, we found that prophylactic treatment with oseltamivir significantly reduced the risk for infection per farm visit from 0.145 (95% confidence interval [CI] 0.078–0.233) to 0.031 (95% CI 0.008–0.073). The protective effect was ≈79% (95% CI 40%–97%). These results are comparable with the reported effect of prophylactic treatment with oseltamivir on human seasonal influenza. No significant protective effect was found for use of respirators or safety glasses, possibly because of limitations of the data. |
| first_indexed | 2024-12-12T22:27:07Z |
| format | Article |
| id | doaj.art-c4c54bbecfae40a5a2f64055275804e4 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-12T22:27:07Z |
| publishDate | 2010-10-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-c4c54bbecfae40a5a2f64055275804e42022-12-22T00:09:43ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592010-10-0116101562156810.3201/eid1610.091412Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003Dennis E. te BeestMichiel van BovenMarian E.H. BosArjan StegemanMarion P.G. KoopmansWe analyzed the effectiveness of personal protective equipment and oseltamivir use during the 2003 avian influenza A (H7N7) epidemic in the Netherlands by linking databases containing information about farm visits, human infections, and use of oseltamivir and personal protective equipment. Using a stringent case definition, based on self-reported conjunctivitis combined with a positive hemagglutination-inhibition assay, we found that prophylactic treatment with oseltamivir significantly reduced the risk for infection per farm visit from 0.145 (95% confidence interval [CI] 0.078–0.233) to 0.031 (95% CI 0.008–0.073). The protective effect was ≈79% (95% CI 40%–97%). These results are comparable with the reported effect of prophylactic treatment with oseltamivir on human seasonal influenza. No significant protective effect was found for use of respirators or safety glasses, possibly because of limitations of the data.https://wwwnc.cdc.gov/eid/article/16/10/09-1412_articleAvian influenzazoonosespoultryhuman infectionpersonal protective measuresantiviral |
| spellingShingle | Dennis E. te Beest Michiel van Boven Marian E.H. Bos Arjan Stegeman Marion P.G. Koopmans Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 Emerging Infectious Diseases Avian influenza zoonoses poultry human infection personal protective measures antiviral |
| title | Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 |
| title_full | Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 |
| title_fullStr | Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 |
| title_full_unstemmed | Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 |
| title_short | Effectiveness of Personal Protective Equipment and Oseltamivir Prophylaxis during Avian Influenza A (H7N7) Epidemic, the Netherlands, 2003 |
| title_sort | effectiveness of personal protective equipment and oseltamivir prophylaxis during avian influenza a h7n7 epidemic the netherlands 2003 |
| topic | Avian influenza zoonoses poultry human infection personal protective measures antiviral |
| url | https://wwwnc.cdc.gov/eid/article/16/10/09-1412_article |
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