Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation
Background: Uterus transplantation may offer women with absolute uterine infertility the chance for gestational motherhood. Infertility treatment can be associated with psychological distress and the absolute nature of infertility in these women could heighten the risk. While uterus transplantation...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2022-09-01
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| Series: | Fertility & Reproduction |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S2661318222741157 |
| _version_ | 1797985125358632960 |
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| author | Jana PITTMAN Natalie MORRISON Lise MOGENSEN Rebecca DEANS |
| author_facet | Jana PITTMAN Natalie MORRISON Lise MOGENSEN Rebecca DEANS |
| author_sort | Jana PITTMAN |
| collection | DOAJ |
| description | Background: Uterus transplantation may offer women with absolute uterine infertility the chance for gestational motherhood. Infertility treatment can be associated with psychological distress and the absolute nature of infertility in these women could heighten the risk. While uterus transplantation is promising the potential repercussion of graft failure and organ availability could have repercussions on these families. Understanding the baseline psychological well-being prior to uterus transplant is needed to support these women. Aim: Explore baseline psychological scores in women with acquired and congenital uterine absence. Method: A survey including demographic data and two-validated tools, DASS21 and FertiQOL was given to two groups, women with congenital uterine absence and those with acquired (hysterectomy). Data was compared between groups for DASS21, and against Boivin et al.1 normative data for women with infertility (FertiQOL). Results: The study included 41 women, (average age 32.6yrs ± 10.4). As a collective only moderate depression, mild anxiety, and mild stress scores were reported however in the congenital uterine absence group 10.5% reported extremely severe anxiety and 5.3% extreme depression. Mean FertiQOL score was 57.76, 3.16 points higher than Boivin’s average. Women with hysterectomy scored on average 15.36 points lower than those with congenital uterine absence. Conclusion: In this study, women with congenital uterine infertility appeared to experience significantly higher levels of depression and anxiety than women post-hysterectomy. The opposite was seen in infertility scores where women with congenital absence reported higher quality of life scores than both the normative values and those post-hysterectomy. It is essential robust psychological screening and support is offered to these women prior to inclusion into a uterus transplant program. |
| first_indexed | 2024-04-11T07:13:47Z |
| format | Article |
| id | doaj.art-c4c626314fad4702a01df7d914a4aee5 |
| institution | Directory Open Access Journal |
| issn | 2661-3182 2661-3174 |
| language | English |
| last_indexed | 2024-04-11T07:13:47Z |
| publishDate | 2022-09-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Fertility & Reproduction |
| spelling | doaj.art-c4c626314fad4702a01df7d914a4aee52022-12-22T04:38:05ZengWorld Scientific PublishingFertility & Reproduction2661-31822661-31742022-09-010403n0420420410.1142/S2661318222741157Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus TransplantationJana PITTMAN0Natalie MORRISON1Lise MOGENSEN2Rebecca DEANS3University of New South Wales, Sydney, AustraliaWestern Sydney University, Campbelltown, AustraliaWestern Sydney University, Campbelltown, AustraliaUniversity of New South Wales, Sydney, AustraliaBackground: Uterus transplantation may offer women with absolute uterine infertility the chance for gestational motherhood. Infertility treatment can be associated with psychological distress and the absolute nature of infertility in these women could heighten the risk. While uterus transplantation is promising the potential repercussion of graft failure and organ availability could have repercussions on these families. Understanding the baseline psychological well-being prior to uterus transplant is needed to support these women. Aim: Explore baseline psychological scores in women with acquired and congenital uterine absence. Method: A survey including demographic data and two-validated tools, DASS21 and FertiQOL was given to two groups, women with congenital uterine absence and those with acquired (hysterectomy). Data was compared between groups for DASS21, and against Boivin et al.1 normative data for women with infertility (FertiQOL). Results: The study included 41 women, (average age 32.6yrs ± 10.4). As a collective only moderate depression, mild anxiety, and mild stress scores were reported however in the congenital uterine absence group 10.5% reported extremely severe anxiety and 5.3% extreme depression. Mean FertiQOL score was 57.76, 3.16 points higher than Boivin’s average. Women with hysterectomy scored on average 15.36 points lower than those with congenital uterine absence. Conclusion: In this study, women with congenital uterine infertility appeared to experience significantly higher levels of depression and anxiety than women post-hysterectomy. The opposite was seen in infertility scores where women with congenital absence reported higher quality of life scores than both the normative values and those post-hysterectomy. It is essential robust psychological screening and support is offered to these women prior to inclusion into a uterus transplant program.https://www.worldscientific.com/doi/10.1142/S2661318222741157 |
| spellingShingle | Jana PITTMAN Natalie MORRISON Lise MOGENSEN Rebecca DEANS Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation Fertility & Reproduction |
| title | Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation |
| title_full | Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation |
| title_fullStr | Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation |
| title_full_unstemmed | Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation |
| title_short | Psychological Evaluation of Women with Absolute Uterine Infertility Prior to the Introduction of Uterus Transplantation |
| title_sort | psychological evaluation of women with absolute uterine infertility prior to the introduction of uterus transplantation |
| url | https://www.worldscientific.com/doi/10.1142/S2661318222741157 |
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