A Novel Improved Thromboembolism-Based Rat Stroke Model That Meets the Latest Standards in Preclinical Studies

A Novel Improved Thromboembolism-Based Rat Stroke Model That Meets the Latest Standards in Preclinical Studies

The animal thromboembolic model of ischemia perfectly mimics human ischemic stroke which remains the leading cause of disability and mortality in humans. The development of new treatment strategies was therefore imperative. The purpose of this study is to improve the thromboembolic stroke model in r...

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Bibliographic Details
Main Authors: Katarzyna Pawletko, Halina Jędrzejowska-Szypułka, Katarzyna Bogus, Alessia Pascale, Foroogh Fahmideh, Nicoletta Marchesi, Aniela Grajoszek, Edyta Olakowska, Jarosław Jerzy Barski
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Brain Sciences
Subjects:
focal ischemic stroke
photothrombosis
animal model
motor test
penumbra
Online Access:https://www.mdpi.com/2076-3425/12/12/1671

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