Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans

Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans

Invasive candidiasis (IC) is one of the leading causes of death among immunocompromised patients. Because of limited effective therapy treatment options, prevention of IC through vaccine is an appealing strategy. However, how to induce the generation of direct candidacidal antibodies in host remains...

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Bibliographic Details
Main Authors: Hui Shen, Yuetian Yu, Si-Min Chen, Juan-Juan Sun, Wei Fang, Shi-Yu Guo, Wei-Tong Hou, Xi-Ran Qiu, Yu Zhang, Yuan-Li Chen, Yi-Da Wang, Xin-Yu Hu, Liangjing Lu, Yuan-Ying Jiang, Zui Zou, Mao-Mao An
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
C. albicans
invasive candidiasis
vaccine
antibody
dectin-1
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01648/full

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