Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective
Nanotechnology is an extended investigation field, based on the materials including a size ranging 1-1000 nm.. Numerous polymers are used for the production of nanoparticles. Polylactic acid (PLA), its streo-isomers, such as PLLA and PLDA, and its famous co-polymer polylactic-co-glycolic (PLGA) are...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Iranian Chemical Society
2020-01-01
|
| Series: | Nanochemistry Research |
| Subjects: | |
| Online Access: | http://www.nanochemres.org/article_110491_13d8841bc218dedbb82ce8d84317653c.pdf |
| Summary: | Nanotechnology is an extended investigation field, based on the materials including a size ranging 1-1000 nm.. Numerous polymers are used for the production of nanoparticles. Polylactic acid (PLA), its streo-isomers, such as PLLA and PLDA, and its famous co-polymer polylactic-co-glycolic (PLGA) are among the biocompatible synthetic polymers widely used to produce nanoparticles. These chmeicals are of particular impotance, beacuse they are biocompatible and biodegradable, despite their synthetic nature. A biodegradable polymer is a polymer which is submitted to the degrading procedures in-vivo. The polymeric nanoparticles commonly propose an extended surface area, high drug loading capability, feasibility of functionalization with ligands, controlled drug releasing capacity, minimal toxicity, biocompatibility, storage stability, and flexibility in the management methods. Furthermore, these nanostructure materials signify unique groundbreaking non-invasive methods for delivery structures in biomedical fields such as wound dressing materials, tissue scaffolds, gene-delivery materials, and drug delivery systems for cancer chemo-therapy. |
|---|---|
| ISSN: | 2538-4279 2423-818X |