Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective
Nanotechnology is an extended investigation field, based on the materials including a size ranging 1-1000 nm.. Numerous polymers are used for the production of nanoparticles. Polylactic acid (PLA), its streo-isomers, such as PLLA and PLDA, and its famous co-polymer polylactic-co-glycolic (PLGA) are...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Iranian Chemical Society
2020-01-01
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| Series: | Nanochemistry Research |
| Subjects: | |
| Online Access: | http://www.nanochemres.org/article_110491_13d8841bc218dedbb82ce8d84317653c.pdf |
| _version_ | 1811171976939569152 |
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| author | Farnaz Sadat Fattahi Tahereh Zamani |
| author_facet | Farnaz Sadat Fattahi Tahereh Zamani |
| author_sort | Farnaz Sadat Fattahi |
| collection | DOAJ |
| description | Nanotechnology is an extended investigation field, based on the materials including a size ranging 1-1000 nm.. Numerous polymers are used for the production of nanoparticles. Polylactic acid (PLA), its streo-isomers, such as PLLA and PLDA, and its famous co-polymer polylactic-co-glycolic (PLGA) are among the biocompatible synthetic polymers widely used to produce nanoparticles. These chmeicals are of particular impotance, beacuse they are biocompatible and biodegradable, despite their synthetic nature. A biodegradable polymer is a polymer which is submitted to the degrading procedures in-vivo. The polymeric nanoparticles commonly propose an extended surface area, high drug loading capability, feasibility of functionalization with ligands, controlled drug releasing capacity, minimal toxicity, biocompatibility, storage stability, and flexibility in the management methods. Furthermore, these nanostructure materials signify unique groundbreaking non-invasive methods for delivery structures in biomedical fields such as wound dressing materials, tissue scaffolds, gene-delivery materials, and drug delivery systems for cancer chemo-therapy. |
| first_indexed | 2024-04-10T17:24:08Z |
| format | Article |
| id | doaj.art-c4cf54ecf0f54ca9bc16c198edb11ad6 |
| institution | Directory Open Access Journal |
| issn | 2538-4279 2423-818X |
| language | English |
| last_indexed | 2024-04-10T17:24:08Z |
| publishDate | 2020-01-01 |
| publisher | Iranian Chemical Society |
| record_format | Article |
| series | Nanochemistry Research |
| spelling | doaj.art-c4cf54ecf0f54ca9bc16c198edb11ad62023-02-05T07:23:39ZengIranian Chemical SocietyNanochemistry Research2538-42792423-818X2020-01-015111310.22036/ncr.2020.01.001110491Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific PerspectiveFarnaz Sadat Fattahi0Tahereh Zamani1Department of Textile Engineering, Isfahan University of Technology, Isfahan, Iran.The Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.Nanotechnology is an extended investigation field, based on the materials including a size ranging 1-1000 nm.. Numerous polymers are used for the production of nanoparticles. Polylactic acid (PLA), its streo-isomers, such as PLLA and PLDA, and its famous co-polymer polylactic-co-glycolic (PLGA) are among the biocompatible synthetic polymers widely used to produce nanoparticles. These chmeicals are of particular impotance, beacuse they are biocompatible and biodegradable, despite their synthetic nature. A biodegradable polymer is a polymer which is submitted to the degrading procedures in-vivo. The polymeric nanoparticles commonly propose an extended surface area, high drug loading capability, feasibility of functionalization with ligands, controlled drug releasing capacity, minimal toxicity, biocompatibility, storage stability, and flexibility in the management methods. Furthermore, these nanostructure materials signify unique groundbreaking non-invasive methods for delivery structures in biomedical fields such as wound dressing materials, tissue scaffolds, gene-delivery materials, and drug delivery systems for cancer chemo-therapy.http://www.nanochemres.org/article_110491_13d8841bc218dedbb82ce8d84317653c.pdfpolylactic acidnanoparticlesynthesisemulsification evaporationbiomedical |
| spellingShingle | Farnaz Sadat Fattahi Tahereh Zamani Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective Nanochemistry Research polylactic acid nanoparticle synthesis emulsification evaporation biomedical |
| title | Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective |
| title_full | Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective |
| title_fullStr | Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective |
| title_full_unstemmed | Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective |
| title_short | Synthesis of Polylactic Acid Nanoparticles for the Novel Biomedical Applications: A Scientific Perspective |
| title_sort | synthesis of polylactic acid nanoparticles for the novel biomedical applications a scientific perspective |
| topic | polylactic acid nanoparticle synthesis emulsification evaporation biomedical |
| url | http://www.nanochemres.org/article_110491_13d8841bc218dedbb82ce8d84317653c.pdf |
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