Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity

Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity

IntroductionAnti-CD40 agonistic antibody (αCD40), an activator of dendritic cells (DC) can enhance antigen presentation and activate cytotoxic T-cells against poorly immunogenic tumors. However, cancer immunotherapy trials also suggest that αCD40 is only moderately effective in patients, falling sho...

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Bibliographic Details
Main Authors:	Akansha Singh, Ashish Ranjan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Immunology
Subjects:	immunotherapy Anti-CD40 agonist antibody propranalol adrenergic signaling anti-tumor immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1141712/full

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