Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children
Background: Certain specific bacterial species from the subgingival biofilm have demonstrated etiological relevance in the initiation and progression of periodontitis. Among all the bacteria studied, three have shown the highest association with proximal caries and bone loss: Fusobacterium nucleatum...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Saudi Journal of Medicine and Medical Sciences |
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| Online Access: | http://www.sjmms.net/article.asp?issn=1658-631X;year=2016;volume=4;issue=2;spage=98;epage=103;aulast=Alagl |
| _version_ | 1819095343079358464 |
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| author | Adel S Alagl |
| author_facet | Adel S Alagl |
| author_sort | Adel S Alagl |
| collection | DOAJ |
| description | Background: Certain specific bacterial species from the subgingival biofilm have demonstrated etiological relevance in the initiation and progression of periodontitis. Among all the bacteria studied, three have shown the highest association with proximal caries and bone loss: Fusobacterium nucleatum (Fn), Capnocytophaga (Ca), and Campylobacter rectus (Cr). Therefore, the relevance of having accurate microbiological diagnostic techniques for their identification and quantification is clearly justified.
Aim: To identify the bacterial pathogens with alveolar bone loss and proximal caries in primary dentition and their association with periodontal disease utilizing deoxyribonucleic acid (DNA) microbial probe testing.
Materials and Methods: Subgingival plaque samples were collected at baseline as well as at 3, 6, and 12 months later. After extracting DNA, Fn, Ca, Cr, Aggrgatbacter actinomycetemcomitans, Porphyromonas gingivalis and several other periodontopathogens were determined by DNA microbial probe testing method.
Results: Samples detecting a high bacterial load of Fn, Ca and Cr in children having proximal caries associated with periodontal disease compared to children having proximal caries without periodontal disease (P ≤ 0.01).
Conclusions: Results suggested that there was a relationship between microbial pathogens associated with proximal dental caries in the primary dentition and periodontal disease in children. In addition, DNA microbial probe testing technology clearly analyzed the different loads of periodontopathogens in children who had with proximal caries associated with bone loss and is useful in microbial diagnostics for patients in dental practices. |
| first_indexed | 2024-12-21T23:41:47Z |
| format | Article |
| id | doaj.art-c4d7ed1e6c714bd4b09d0517dd78828c |
| institution | Directory Open Access Journal |
| issn | 1658-631X |
| language | English |
| last_indexed | 2024-12-21T23:41:47Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Medicine and Medical Sciences |
| spelling | doaj.art-c4d7ed1e6c714bd4b09d0517dd78828c2022-12-21T18:46:12ZengWolters Kluwer Medknow PublicationsSaudi Journal of Medicine and Medical Sciences1658-631X2016-01-01429810310.4103/1658-631X.178323Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in childrenAdel S AlaglBackground: Certain specific bacterial species from the subgingival biofilm have demonstrated etiological relevance in the initiation and progression of periodontitis. Among all the bacteria studied, three have shown the highest association with proximal caries and bone loss: Fusobacterium nucleatum (Fn), Capnocytophaga (Ca), and Campylobacter rectus (Cr). Therefore, the relevance of having accurate microbiological diagnostic techniques for their identification and quantification is clearly justified. Aim: To identify the bacterial pathogens with alveolar bone loss and proximal caries in primary dentition and their association with periodontal disease utilizing deoxyribonucleic acid (DNA) microbial probe testing. Materials and Methods: Subgingival plaque samples were collected at baseline as well as at 3, 6, and 12 months later. After extracting DNA, Fn, Ca, Cr, Aggrgatbacter actinomycetemcomitans, Porphyromonas gingivalis and several other periodontopathogens were determined by DNA microbial probe testing method. Results: Samples detecting a high bacterial load of Fn, Ca and Cr in children having proximal caries associated with periodontal disease compared to children having proximal caries without periodontal disease (P ≤ 0.01). Conclusions: Results suggested that there was a relationship between microbial pathogens associated with proximal dental caries in the primary dentition and periodontal disease in children. In addition, DNA microbial probe testing technology clearly analyzed the different loads of periodontopathogens in children who had with proximal caries associated with bone loss and is useful in microbial diagnostics for patients in dental practices.http://www.sjmms.net/article.asp?issn=1658-631X;year=2016;volume=4;issue=2;spage=98;epage=103;aulast=AlaglPeriodontal pathogensperiodontal disease in childrenproximal dental caries |
| spellingShingle | Adel S Alagl Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children Saudi Journal of Medicine and Medical Sciences Periodontal pathogens periodontal disease in children proximal dental caries |
| title | Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| title_full | Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| title_fullStr | Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| title_full_unstemmed | Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| title_short | Microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| title_sort | microbial pathogens associated with proximal dental caries in the primary dentition and their association with periodontal disease in children |
| topic | Periodontal pathogens periodontal disease in children proximal dental caries |
| url | http://www.sjmms.net/article.asp?issn=1658-631X;year=2016;volume=4;issue=2;spage=98;epage=103;aulast=Alagl |
| work_keys_str_mv | AT adelsalagl microbialpathogensassociatedwithproximaldentalcariesintheprimarydentitionandtheirassociationwithperiodontaldiseaseinchildren |