Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives
Different genome editing approaches have been used to engineer resistance against plant viruses. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas; CRISPR/Cas) systems to create pinpoint genetic mutations have emerged as a powerful tool for molecul...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.904829/full |
| _version_ | 1818228491145969664 |
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| author | Fredy D. A. Silva Elizabeth P. B. Fontes |
| author_facet | Fredy D. A. Silva Elizabeth P. B. Fontes |
| author_sort | Fredy D. A. Silva |
| collection | DOAJ |
| description | Different genome editing approaches have been used to engineer resistance against plant viruses. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas; CRISPR/Cas) systems to create pinpoint genetic mutations have emerged as a powerful tool for molecular engineering of plant immunity and increasing resistance against plant viruses. This review presents (i) recent advances in engineering resistance against plant viruses by CRISPR/Cas and (ii) an overview of the potential host factors as targets for the CRISPR/Cas system-mediated broad-range resistance and immunity. Applications, challenges, and perspectives in enabling the CRISPR/Cas system for crop protection are also outlined. |
| first_indexed | 2024-12-12T10:03:33Z |
| format | Article |
| id | doaj.art-c4df589eaac642059527042b3cf5e49d |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-12T10:03:33Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-c4df589eaac642059527042b3cf5e49d2022-12-22T00:27:57ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2022-05-011310.3389/fpls.2022.904829904829Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and PerspectivesFredy D. A. SilvaElizabeth P. B. FontesDifferent genome editing approaches have been used to engineer resistance against plant viruses. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas; CRISPR/Cas) systems to create pinpoint genetic mutations have emerged as a powerful tool for molecular engineering of plant immunity and increasing resistance against plant viruses. This review presents (i) recent advances in engineering resistance against plant viruses by CRISPR/Cas and (ii) an overview of the potential host factors as targets for the CRISPR/Cas system-mediated broad-range resistance and immunity. Applications, challenges, and perspectives in enabling the CRISPR/Cas system for crop protection are also outlined.https://www.frontiersin.org/articles/10.3389/fpls.2022.904829/fullCRISPR/Casgenome editingresistance to virusessusceptibility genesvirus-host interactionsplant antiviral immunity |
| spellingShingle | Fredy D. A. Silva Elizabeth P. B. Fontes Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives Frontiers in Plant Science CRISPR/Cas genome editing resistance to viruses susceptibility genes virus-host interactions plant antiviral immunity |
| title | Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives |
| title_full | Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives |
| title_fullStr | Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives |
| title_full_unstemmed | Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives |
| title_short | Clustered Regularly Interspaced Short Palindromic Repeats-Associated Protein System for Resistance Against Plant Viruses: Applications and Perspectives |
| title_sort | clustered regularly interspaced short palindromic repeats associated protein system for resistance against plant viruses applications and perspectives |
| topic | CRISPR/Cas genome editing resistance to viruses susceptibility genes virus-host interactions plant antiviral immunity |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2022.904829/full |
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