Role of Mineralocorticoid and Angiotensin Type 1 Receptors in the Paraventricular Nucleus in Angiotensin-Induced Hypertension

Role of Mineralocorticoid and Angiotensin Type 1 Receptors in the Paraventricular Nucleus in Angiotensin-Induced Hypertension

The hypothalamic paraventricular nucleus (PVN) is an important site where an interaction between circulating angiotensin (Ang) and mineralocorticoid receptor (MR) activity may modify sympathetic nerve activity (SNA) to influence long-term elevation of blood pressure. We examined in conscious Ang II-...

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Bibliographic Details
Main Authors: Sandra L. Burke, Benjamin Barzel, Kristy L. Jackson, Cindy Gueguen, Morag J. Young, Geoffrey A. Head
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
hypertension
sympathetic nerve activity
angiotensin II
aldosterone
RU28318
rabbit
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.640373/full

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