Hyperthermia as a Potential Cornerstone of Effective Multimodality Treatment with Radiotherapy, Cisplatin and PARP Inhibitor in <i>IDH1</i>-Mutated Cancer Cells

Hyperthermia as a Potential Cornerstone of Effective Multimodality Treatment with Radiotherapy, Cisplatin and PARP Inhibitor in <i>IDH1</i>-Mutated Cancer Cells

Mutations in the isocitrate dehydrogenase 1 (<i>IDH1</i><sup>MUT</sup>) gene occur in various types of malignancies, including ~60% of chondrosarcomas, ~30% of intrahepatic cholangiocarcinomas and >80% of low-grade gliomas. <i>IDH1</i><sup>MUT</sup>...

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Bibliographic Details
Main Authors: Mohammed Khurshed, Elia Prades-Sagarra, Sarah Saleh, Peter Sminia, Johanna W. Wilmink, Remco J. Molenaar, Hans Crezee, Cornelis J. F. van Noorden
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
isocitrate dehydrogenase
PARP
hyperthermia
<i>D</i>-2-hydroxyglutarate
radiotherapy
cisplatin
Online Access:https://www.mdpi.com/2072-6694/14/24/6228

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