Peptide-based Synthetic Design, Construction and Morphology of Soft Structures
Peptide-based self-assembly offers a unique entry into the construction of soft structures with interesting material properties and functions. Aromatic amino acid-containing peptides are commonly employed as they exhibit high propensity to aggregate due to increased hydrophobic content, pr...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2012-12-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://www.chimia.ch/chimia/article/view/5321 |
| _version_ | 1818282295716478976 |
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| author | Sudipta Mondal Apurba K. Barman Sandeep Verma |
| author_facet | Sudipta Mondal Apurba K. Barman Sandeep Verma |
| author_sort | Sudipta Mondal |
| collection | DOAJ |
| description |
Peptide-based self-assembly offers a unique entry into the construction of soft structures with interesting material properties and functions. Aromatic amino acid-containing peptides are commonly employed as they exhibit high propensity to aggregate due to increased hydrophobic content,
promotion of favorable secondary structures, planarity and the possibility of ?–? interactions. Incorporation of covalent scaffolds, stimuli-responsive handles and carbohydrate moieties augment beneficial characteristics to the resulting peptide conjugates. These modifications
were shown to enforce self-association, elicit stimuli response and achieve improved hydrophilic properties, to name but a few.
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| first_indexed | 2024-12-13T00:18:45Z |
| format | Article |
| id | doaj.art-c4e82c418def489ab67b1d6167716c33 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-13T00:18:45Z |
| publishDate | 2012-12-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-c4e82c418def489ab67b1d6167716c332022-12-22T00:05:41ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242012-12-01661210.2533/chimia.2012.930Peptide-based Synthetic Design, Construction and Morphology of Soft StructuresSudipta Mondal0Apurba K. Barman1Sandeep Verma2Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur – 208016 (UP) IndiaDepartment of Chemistry, Indian Institute of Technology Kanpur, Kanpur – 208016 (UP) IndiaDepartment of Chemistry, Indian Institute of Technology Kanpur, Kanpur – 208016 (UP) India; DST Thematic Unit of Excellence on Soft Nanofabrication, Indian Institute of Technology Kanpur, Kanpur – 208016 (UP) India. sverma@iitk.ac.in Peptide-based self-assembly offers a unique entry into the construction of soft structures with interesting material properties and functions. Aromatic amino acid-containing peptides are commonly employed as they exhibit high propensity to aggregate due to increased hydrophobic content, promotion of favorable secondary structures, planarity and the possibility of ?–? interactions. Incorporation of covalent scaffolds, stimuli-responsive handles and carbohydrate moieties augment beneficial characteristics to the resulting peptide conjugates. These modifications were shown to enforce self-association, elicit stimuli response and achieve improved hydrophilic properties, to name but a few. https://www.chimia.ch/chimia/article/view/5321CarbohydratesFibersPeptide conjugatesScaffoldsSelf-assemblyVesicles |
| spellingShingle | Sudipta Mondal Apurba K. Barman Sandeep Verma Peptide-based Synthetic Design, Construction and Morphology of Soft Structures CHIMIA Carbohydrates Fibers Peptide conjugates Scaffolds Self-assembly Vesicles |
| title | Peptide-based Synthetic Design, Construction and Morphology of Soft Structures |
| title_full | Peptide-based Synthetic Design, Construction and Morphology of Soft Structures |
| title_fullStr | Peptide-based Synthetic Design, Construction and Morphology of Soft Structures |
| title_full_unstemmed | Peptide-based Synthetic Design, Construction and Morphology of Soft Structures |
| title_short | Peptide-based Synthetic Design, Construction and Morphology of Soft Structures |
| title_sort | peptide based synthetic design construction and morphology of soft structures |
| topic | Carbohydrates Fibers Peptide conjugates Scaffolds Self-assembly Vesicles |
| url | https://www.chimia.ch/chimia/article/view/5321 |
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