Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings

Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings

Abstract Background As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable methods for genotyping all relevant HIV-1 pol genes (i.e., protease (PR), reverse transcriptase (RT) and integrase (IN)) are...

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Bibliographic Details
Main Authors: Sontaga Manyana, Melendhran Pillay, Lilishia Gounder, Aabida Khan, Pravi Moodley, Kogieleum Naidoo, Benjamin Chimukangara
Format: Article
Language:English
Published: BMC 2023-02-01
Series:AIDS Research and Therapy
Subjects:
HIV-1
Pol gene
Affordable genotypic testing
Drug resistance
Resource limited settings
Primary integrase resistance
Online Access:https://doi.org/10.1186/s12981-023-00505-3

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