Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs
Use of class I antiarrhythmic drugs in the elderly is limited by their adverse drug reactions (ADRs), proarrhythmic effect (I A и I C) and high risk of drug interactions. Disopyramide use should be avoided due to its strong anticholinergic properties associated with the risk of cognitive and physica...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-09-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/1313 |
| _version_ | 1797232252333064192 |
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| author | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva |
| author_facet | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva |
| author_sort | E. A. Ushkalova |
| collection | DOAJ |
| description | Use of class I antiarrhythmic drugs in the elderly is limited by their adverse drug reactions (ADRs), proarrhythmic effect (I A и I C) and high risk of drug interactions. Disopyramide use should be avoided due to its strong anticholinergic properties associated with the risk of cognitive and physical disorders and falls in the “very elderly” patients. Available data suggest that elderly patients do not have significant limitations for beta-blockers use. However to determine beta-blockers with the best benefit/risk ratio in elderly patients with co-morbidity further clinical trials are needed. |
| first_indexed | 2024-03-08T14:03:26Z |
| format | Article |
| id | doaj.art-c4f2ec73c11b4a6ab0bde1403de06477 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:57:19Z |
| publishDate | 2016-09-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-c4f2ec73c11b4a6ab0bde1403de064772024-04-01T07:43:34ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-09-0112447147810.20996/1819-6446-2016-12-4-471-4781247Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugsE. A. Ushkalova0S. K. Zyryanov1K. E. Zatolochina2A. P. Pereverzev3N. A. Chukhareva4People's Friendship University of RussiaPeople's Friendship University of RussiaPeople's Friendship University of RussiaPeople's Friendship University of RussiaScientific Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. KulakovUse of class I antiarrhythmic drugs in the elderly is limited by their adverse drug reactions (ADRs), proarrhythmic effect (I A и I C) and high risk of drug interactions. Disopyramide use should be avoided due to its strong anticholinergic properties associated with the risk of cognitive and physical disorders and falls in the “very elderly” patients. Available data suggest that elderly patients do not have significant limitations for beta-blockers use. However to determine beta-blockers with the best benefit/risk ratio in elderly patients with co-morbidity further clinical trials are needed.https://www.rpcardio.online/jour/article/view/1313class i and ii antiarrhythmic drugselderly patients |
| spellingShingle | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs Рациональная фармакотерапия в кардиологии class i and ii antiarrhythmic drugs elderly patients |
| title | Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs |
| title_full | Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs |
| title_fullStr | Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs |
| title_full_unstemmed | Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs |
| title_short | Antiarrhythmic drugs use in elderly patients. Vaughan Williams class I and II drugs |
| title_sort | antiarrhythmic drugs use in elderly patients vaughan williams class i and ii drugs |
| topic | class i and ii antiarrhythmic drugs elderly patients |
| url | https://www.rpcardio.online/jour/article/view/1313 |
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