Structural basis for ligand recognition and activation of the prostanoid receptors

Structural basis for ligand recognition and activation of the prostanoid receptors

Summary: Prostaglandin F2α (PGF2α) and thromboxane A2 (TXA2) are endogenous arachidonic acid metabolites, modulating diverse physiological processes including inflammation and cardiovascular homeostasis through activating PGF2α receptor (FP) and TXA2 receptor (TP). Ligands targeting FP and TP have d...

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Bibliographic Details
Main Authors: Xiu Li, Xuan Zhang, Xin Wen, Daolai Zhang, Changxiu Qu, Xinyi Miao, Wenkai Zhang, Ru Zhang, Guibing Liu, Peng Xiao, Jin-Peng Sun, Weimin Gong
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724002213

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