Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study
Green synthesis has recently attracted extensive attention from scientists all over the world for the production of metal nanoparticles. Selenium nanoparticles (Se NPs) have been demonstrated as a suitable supplement nutrient for the replacement of selenium ions in terms of safety and efficiency. Th...
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MDPI AG
2022-10-01
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| Series: | Journal of Composites Science |
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| Online Access: | https://www.mdpi.com/2504-477X/6/10/307 |
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| author | Tri Thien Vu Phuong Thi Mai Nguyen Ngan Hanh Pham Thanh Huu Le Tran Hung Nguyen Dinh Trung Do Duong Duc La |
| author_facet | Tri Thien Vu Phuong Thi Mai Nguyen Ngan Hanh Pham Thanh Huu Le Tran Hung Nguyen Dinh Trung Do Duong Duc La |
| author_sort | Tri Thien Vu |
| collection | DOAJ |
| description | Green synthesis has recently attracted extensive attention from scientists all over the world for the production of metal nanoparticles. Selenium nanoparticles (Se NPs) have been demonstrated as a suitable supplement nutrient for the replacement of selenium ions in terms of safety and efficiency. This work presented a friendly and facile approach to synthesize the Se NPs using polyphenols content in the <i>Cleistocalyx operculatus</i> (CO) leaves extract. The synthesizing conditions were optimized to obtain the Se NPs with uniform distribution and shape. The prepared Se NPs were well-characterized using scanning electron microscopy, X-ray diffraction, energy diffractive spectroscopy, and Fourier-transform infrared spectroscopy. The resultant Se NPs were in spherical shape with the particle size in a range from 50–200 nm. The antimicrobial properties of Se NPs were investigated against <i>Echerichia coli</i> and <i>Staphylococcus aureus,</i> which showed reasonable activity. The acute oral toxicity of Se NPs in mice was also studied. The result indicated that Se NPs exhibited lower toxicity than that of SeO<sub>2</sub> with the lethal concentration (50% death of mice) of 7.75 mg kg<sup>−1</sup><sub>.</sub> |
| first_indexed | 2024-03-09T20:03:14Z |
| format | Article |
| id | doaj.art-c4f7c95e6e334e56be375d342c23e777 |
| institution | Directory Open Access Journal |
| issn | 2504-477X |
| language | English |
| last_indexed | 2024-03-09T20:03:14Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Composites Science |
| spelling | doaj.art-c4f7c95e6e334e56be375d342c23e7772023-11-24T00:41:12ZengMDPI AGJournal of Composites Science2504-477X2022-10-0161030710.3390/jcs6100307Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity StudyTri Thien Vu0Phuong Thi Mai Nguyen1Ngan Hanh Pham2Thanh Huu Le3Tran Hung Nguyen4Dinh Trung Do5Duong Duc La6Institute of Chemistry and Materials, Nghia Do, Cau Giay, Hanoi 100000, VietnamInstitute of Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 100000, VietnamFaculty of Chemistry, Hanoi National University of Education, 136 Xuan Thuy, Dich Vong Hau, Cau Giay, Hanoi 100000, VietnamInstitute of Chemistry and Materials, Nghia Do, Cau Giay, Hanoi 100000, VietnamInstitute of Chemistry and Materials, Nghia Do, Cau Giay, Hanoi 100000, VietnamInstitute of Tropical Durability, Joint Vietnam-Russia Tropical Science and Technology Research Center, Nghia Do, Hanoi 100000, VietnamInstitute of Chemistry and Materials, Nghia Do, Cau Giay, Hanoi 100000, VietnamGreen synthesis has recently attracted extensive attention from scientists all over the world for the production of metal nanoparticles. Selenium nanoparticles (Se NPs) have been demonstrated as a suitable supplement nutrient for the replacement of selenium ions in terms of safety and efficiency. This work presented a friendly and facile approach to synthesize the Se NPs using polyphenols content in the <i>Cleistocalyx operculatus</i> (CO) leaves extract. The synthesizing conditions were optimized to obtain the Se NPs with uniform distribution and shape. The prepared Se NPs were well-characterized using scanning electron microscopy, X-ray diffraction, energy diffractive spectroscopy, and Fourier-transform infrared spectroscopy. The resultant Se NPs were in spherical shape with the particle size in a range from 50–200 nm. The antimicrobial properties of Se NPs were investigated against <i>Echerichia coli</i> and <i>Staphylococcus aureus,</i> which showed reasonable activity. The acute oral toxicity of Se NPs in mice was also studied. The result indicated that Se NPs exhibited lower toxicity than that of SeO<sub>2</sub> with the lethal concentration (50% death of mice) of 7.75 mg kg<sup>−1</sup><sub>.</sub>https://www.mdpi.com/2504-477X/6/10/307selenium nanoparticles<i>Cleistocalyx operculatus</i>green synthesisacute toxicityanti-bacterial |
| spellingShingle | Tri Thien Vu Phuong Thi Mai Nguyen Ngan Hanh Pham Thanh Huu Le Tran Hung Nguyen Dinh Trung Do Duong Duc La Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study Journal of Composites Science selenium nanoparticles <i>Cleistocalyx operculatus</i> green synthesis acute toxicity anti-bacterial |
| title | Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study |
| title_full | Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study |
| title_fullStr | Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study |
| title_full_unstemmed | Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study |
| title_short | Green Synthesis of Selenium Nanoparticles Using <i>Cleistocalyx operculatus</i> Leaf Extract and Their Acute Oral Toxicity Study |
| title_sort | green synthesis of selenium nanoparticles using i cleistocalyx operculatus i leaf extract and their acute oral toxicity study |
| topic | selenium nanoparticles <i>Cleistocalyx operculatus</i> green synthesis acute toxicity anti-bacterial |
| url | https://www.mdpi.com/2504-477X/6/10/307 |
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