Enantioseparation, quantification, molecular docking and molecular dynamics study of five β-adrenergic blockers on Lux-Cellulose-2 column

Enantioseparation, quantification, molecular docking and molecular dynamics study of five β-adrenergic blockers on Lux-Cellulose-2 column

Abstract Enantioseparation of five β-adrenergic blockers was studied using two mobile phases on a cellulose tris(3‐chloro‐4‐methylphenylcarbamate) (Lux-Cellulose-2) chiral column in normal phase mode. The first mobile phase composed of n-hexane: ethanol: diethylamine 60: 40: 0.1 by volume has succes...

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Bibliographic Details
Main Authors: Ola Ahmed Saleh, Amr Mohamed Badawey, Hassan Y. Aboul-Enein, Marwa Ahmed Fouad
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Chemistry
Subjects:
Lux-Cellulose-2 chiral column
Enantioseparation
β-adrenergic blockers
HPLC
Molecular docking
Molecular dynamics
Online Access:https://doi.org/10.1186/s13065-023-00925-2

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