A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome
<p>Abstract</p> <p>Background</p> <p>Individuals who carry deleterious BRCA mutations face significantly elevated risks of breast, ovarian, and other cancers. These individuals are also responsible for informing relatives of their increased risk for carrying the family...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-04-01
|
| Series: | Hereditary Cancer in Clinical Practice |
| Subjects: | |
| Online Access: | http://www.hccpjournal.com/content/10/1/4 |
| _version_ | 1818690949024317440 |
|---|---|
| author | Kardashian Ani Fehniger Julia Creasman Jennifer Cheung Eleanor Beattie Mary |
| author_facet | Kardashian Ani Fehniger Julia Creasman Jennifer Cheung Eleanor Beattie Mary |
| author_sort | Kardashian Ani |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Individuals who carry deleterious BRCA mutations face significantly elevated risks of breast, ovarian, and other cancers. These individuals are also responsible for informing relatives of their increased risk for carrying the family BRCA mutation. Few interventions have been developed to facilitate this family communication process.</p> <p>Methods</p> <p>We developed the Sharing Risk Information Tool (ShaRIT), a personalized educational intervention, to support BRCA carriers as they discuss BRCA positive results and their implications with relatives. We conducted a pilot study of 19 BRCA carriers identified through the University of California San Francisco Cancer Risk Program. Our study had two aims: 1) to assess the feasibility and acceptability of ShaRIT, and 2) describe characteristics associated with increased family communication and BRCA testing. Participants in our study were divided into two groups: those who had not received ShaRIT as part of their genetic counseling protocol (control group, n = 10) and those who received ShaRIT (n = 9).</p> <p>Results</p> <p>All 9 women who received ShaRIT reported that it was a useful resource. Characteristics associated with increased sharing and testing included: female gender, degree of relationship, and frequency of communication. Increased pedigree knowledge showed a trend toward higher rates of sharing.</p> <p>Conclusions</p> <p>Both participants and genetic counselors considered ShaRIT a well-received, comprehensive tool for disseminating individual risk information and clinical care guidelines to Hereditary Breast and Ovarian Cancer Syndrome families. Because of this, ShaRIT has been incorporated as standard of care at our institution. In the future we hope to evaluate the effects of ShaRIT on family communication and family testing in larger populations of BRCA positive families.</p> |
| first_indexed | 2024-12-17T12:34:07Z |
| format | Article |
| id | doaj.art-c4f8fc964a0f43b5942aaf1b2af6296f |
| institution | Directory Open Access Journal |
| issn | 1897-4287 |
| language | English |
| last_indexed | 2024-12-17T12:34:07Z |
| publishDate | 2012-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Hereditary Cancer in Clinical Practice |
| spelling | doaj.art-c4f8fc964a0f43b5942aaf1b2af6296f2022-12-21T21:48:26ZengBMCHereditary Cancer in Clinical Practice1897-42872012-04-01101410.1186/1897-4287-10-4A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer SyndromeKardashian AniFehniger JuliaCreasman JenniferCheung EleanorBeattie Mary<p>Abstract</p> <p>Background</p> <p>Individuals who carry deleterious BRCA mutations face significantly elevated risks of breast, ovarian, and other cancers. These individuals are also responsible for informing relatives of their increased risk for carrying the family BRCA mutation. Few interventions have been developed to facilitate this family communication process.</p> <p>Methods</p> <p>We developed the Sharing Risk Information Tool (ShaRIT), a personalized educational intervention, to support BRCA carriers as they discuss BRCA positive results and their implications with relatives. We conducted a pilot study of 19 BRCA carriers identified through the University of California San Francisco Cancer Risk Program. Our study had two aims: 1) to assess the feasibility and acceptability of ShaRIT, and 2) describe characteristics associated with increased family communication and BRCA testing. Participants in our study were divided into two groups: those who had not received ShaRIT as part of their genetic counseling protocol (control group, n = 10) and those who received ShaRIT (n = 9).</p> <p>Results</p> <p>All 9 women who received ShaRIT reported that it was a useful resource. Characteristics associated with increased sharing and testing included: female gender, degree of relationship, and frequency of communication. Increased pedigree knowledge showed a trend toward higher rates of sharing.</p> <p>Conclusions</p> <p>Both participants and genetic counselors considered ShaRIT a well-received, comprehensive tool for disseminating individual risk information and clinical care guidelines to Hereditary Breast and Ovarian Cancer Syndrome families. Because of this, ShaRIT has been incorporated as standard of care at our institution. In the future we hope to evaluate the effects of ShaRIT on family communication and family testing in larger populations of BRCA positive families.</p>http://www.hccpjournal.com/content/10/1/4Family communicationGenetic testingHereditary breast and ovarian cancer syndromeBRCA1BRCA2 |
| spellingShingle | Kardashian Ani Fehniger Julia Creasman Jennifer Cheung Eleanor Beattie Mary A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome Hereditary Cancer in Clinical Practice Family communication Genetic testing Hereditary breast and ovarian cancer syndrome BRCA1 BRCA2 |
| title | A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome |
| title_full | A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome |
| title_fullStr | A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome |
| title_full_unstemmed | A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome |
| title_short | A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome |
| title_sort | pilot study of the sharing risk information tool sharit for families with hereditary breast and ovarian cancer syndrome |
| topic | Family communication Genetic testing Hereditary breast and ovarian cancer syndrome BRCA1 BRCA2 |
| url | http://www.hccpjournal.com/content/10/1/4 |
| work_keys_str_mv | AT kardashianani apilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT fehnigerjulia apilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT creasmanjennifer apilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT cheungeleanor apilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT beattiemary apilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT kardashianani pilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT fehnigerjulia pilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT creasmanjennifer pilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT cheungeleanor pilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome AT beattiemary pilotstudyofthesharingriskinformationtoolsharitforfamilieswithhereditarybreastandovariancancersyndrome |