Dexmedetomidine modulates neuronal activity of horizontal limbs of diagonal band via α2 adrenergic receptor in mice

Dexmedetomidine modulates neuronal activity of horizontal limbs of diagonal band via α2 adrenergic receptor in mice

Abstract Background and objectives Dexmedetomidine (DEX) is widely used in clinical sedation which has little effect on cardiopulmonary inhibition, however the mechanism remains to be elucidated. The basal forebrain (BF) is a key nucleus that controls sleep-wake cycle. The horizontal limbs of diagon...

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Bibliographic Details
Main Authors: Xia-wei Zhang, Lei Chen, Chang-feng Chen, Juan Cheng, Ping-ping Zhang, Lie-cheng Wang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Basal forebrain
Horizontal limbs of diagonal bundle
α2 adrenergic receptor
Online Access:https://doi.org/10.1186/s12871-023-02278-8

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