A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy
Neuronal intranuclear inclusion disease (NIID) is a relatively new entity identified as a progressive neurodegenerative disease characterised by eosinophilic hyaline intranuclear inclusions widely observed in neuronal and somatic cells. Renal biopsy from one of our patients with NIID showed lupus ne...
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Format: | Article |
Language: | English |
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Elsevier
2018-03-01
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Series: | eNeurologicalSci |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650218300029 |
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author | Taro Horino Tatsuki Matsumoto Kosuke Inoue Osamu Ichii Yoshio Terada |
author_facet | Taro Horino Tatsuki Matsumoto Kosuke Inoue Osamu Ichii Yoshio Terada |
author_sort | Taro Horino |
collection | DOAJ |
description | Neuronal intranuclear inclusion disease (NIID) is a relatively new entity identified as a progressive neurodegenerative disease characterised by eosinophilic hyaline intranuclear inclusions widely observed in neuronal and somatic cells. Renal biopsy from one of our patients with NIID showed lupus nephritis–like pathology. He was treated with steroids and angiotensin-converting enzyme inhibitors and his proteinuria improved. The present case highlights that immune-mediated glomerulonephritis can be a presenting feature of NIID, which can be controlled with proper treatment. Keywords: Neuronal intranuclear inclusion disease, Lupus nephritis–like nephropathy |
first_indexed | 2024-12-17T07:42:37Z |
format | Article |
id | doaj.art-c5042c79a2644331ad5488dd2d9838a6 |
institution | Directory Open Access Journal |
issn | 2405-6502 |
language | English |
last_indexed | 2024-12-17T07:42:37Z |
publishDate | 2018-03-01 |
publisher | Elsevier |
record_format | Article |
series | eNeurologicalSci |
spelling | doaj.art-c5042c79a2644331ad5488dd2d9838a62022-12-21T21:58:06ZengElseviereNeurologicalSci2405-65022018-03-01102830A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathyTaro Horino0Tatsuki Matsumoto1Kosuke Inoue2Osamu Ichii3Yoshio Terada4Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, Japan; Corresponding author at: Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan.Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, JapanDepartment of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, JapanLaboratory of Anatomy, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, JapanDepartment of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, JapanNeuronal intranuclear inclusion disease (NIID) is a relatively new entity identified as a progressive neurodegenerative disease characterised by eosinophilic hyaline intranuclear inclusions widely observed in neuronal and somatic cells. Renal biopsy from one of our patients with NIID showed lupus nephritis–like pathology. He was treated with steroids and angiotensin-converting enzyme inhibitors and his proteinuria improved. The present case highlights that immune-mediated glomerulonephritis can be a presenting feature of NIID, which can be controlled with proper treatment. Keywords: Neuronal intranuclear inclusion disease, Lupus nephritis–like nephropathyhttp://www.sciencedirect.com/science/article/pii/S2405650218300029 |
spellingShingle | Taro Horino Tatsuki Matsumoto Kosuke Inoue Osamu Ichii Yoshio Terada A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy eNeurologicalSci |
title | A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy |
title_full | A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy |
title_fullStr | A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy |
title_full_unstemmed | A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy |
title_short | A case of neuronal intranuclear inclusion disease associated with lupus nephritis–like nephropathy |
title_sort | case of neuronal intranuclear inclusion disease associated with lupus nephritis like nephropathy |
url | http://www.sciencedirect.com/science/article/pii/S2405650218300029 |
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