Structural Dynamics and Molecular Evolution of the SARS-CoV-2 Spike Protein

Structural Dynamics and Molecular Evolution of the SARS-CoV-2 Spike Protein

ABSTRACT The ongoing coronavirus disease 2019 (COVID-19) pandemic demonstrates the threat posed by novel coronaviruses to human health. Coronaviruses share a highly conserved cell entry mechanism mediated by the spike protein, the sole product of the S gene. The structural dynamics by which the spik...

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Bibliographic Details
Main Authors: Kyle A. Wolf, Jason C. Kwan, Jeremy P. Kamil
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:mBio
Subjects:
SARS-CoV-2
adaptive mutations
coronavirus
COVID-19
evolution
genomics
Online Access:https://journals.asm.org/doi/10.1128/mbio.02030-21

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