Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study
Background: Amniotic fluid embolism (AFE) is an urgent, catastrophic obstetric complication, but not all medical settings are equipped to manage AFE. The purpose of this study is to summarize the experience of referral of women with AFE in order to save the lives of women and improve the prognosis....
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2023-12-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/50/12/10.31083/j.ceog5012255 |
| _version_ | 1797365402020347904 |
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| author | Huiqin Qian Wei Qian Yixiao Wang Sicong Liu Nathan Obore Yuchen Tao You Lv Chengqian Wu Hong Yu |
| author_facet | Huiqin Qian Wei Qian Yixiao Wang Sicong Liu Nathan Obore Yuchen Tao You Lv Chengqian Wu Hong Yu |
| author_sort | Huiqin Qian |
| collection | DOAJ |
| description | Background: Amniotic fluid embolism (AFE) is an urgent, catastrophic obstetric complication, but not all medical settings are equipped to manage AFE. The purpose of this study is to summarize the experience of referral of women with AFE in order to save the lives of women and improve the prognosis. Methods: We retrospectively collected the demographic characteristics, delivery process, symptoms and test indicators at the onset of AFE, as well as the treatment status and outcomes after referral of women with AFE who were treated at our hospital from January 2015 to November 2022. We descriptively summarized and analyzed these data. Results: A total of 13 women with AFE transferred to our hospital were included in the study. After referral, 3 women (23.08%) eventually died. One of the deceased women presented with hypothermia (34.5 °C) at the time of referral, and all 3 fatalities had lactic acidosis (pH <7.35 and lactic acid ≥5 mmol/L) and hypofibrinogenemia (<2 g/L). All 13 women were in shock after referral to our hospital and 92.31% (12/13) of the women were diagnosed with multiple organ dysfunction (MODS) when they were discharged. The markers of heart failure were abnormally elevated in the 3 deceased women. Conclusions: Referral should be considered as soon as possible in women with lactic acidosis, hypofibrinogenemia, and hypothermia with AFE. |
| first_indexed | 2024-03-08T16:48:22Z |
| format | Article |
| id | doaj.art-c5070ae039d74066be2d4a8b26425da1 |
| institution | Directory Open Access Journal |
| issn | 0390-6663 |
| language | English |
| last_indexed | 2024-03-08T16:48:22Z |
| publishDate | 2023-12-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Clinical and Experimental Obstetrics & Gynecology |
| spelling | doaj.art-c5070ae039d74066be2d4a8b26425da12024-01-05T07:27:09ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632023-12-01501225510.31083/j.ceog5012255S0390-6663(23)02198-XReferral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive StudyHuiqin Qian0Wei Qian1Yixiao Wang2Sicong Liu3Nathan Obore4Yuchen Tao5You Lv6Chengqian Wu7Hong Yu8Department of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, 210000 Nanjing, Jiangsu, ChinaDepartment of Obstetrics and Gynecology, Southeast University Affiliated Zhongda Hospital, 210000 Nanjing, Jiangsu, ChinaBackground: Amniotic fluid embolism (AFE) is an urgent, catastrophic obstetric complication, but not all medical settings are equipped to manage AFE. The purpose of this study is to summarize the experience of referral of women with AFE in order to save the lives of women and improve the prognosis. Methods: We retrospectively collected the demographic characteristics, delivery process, symptoms and test indicators at the onset of AFE, as well as the treatment status and outcomes after referral of women with AFE who were treated at our hospital from January 2015 to November 2022. We descriptively summarized and analyzed these data. Results: A total of 13 women with AFE transferred to our hospital were included in the study. After referral, 3 women (23.08%) eventually died. One of the deceased women presented with hypothermia (34.5 °C) at the time of referral, and all 3 fatalities had lactic acidosis (pH <7.35 and lactic acid ≥5 mmol/L) and hypofibrinogenemia (<2 g/L). All 13 women were in shock after referral to our hospital and 92.31% (12/13) of the women were diagnosed with multiple organ dysfunction (MODS) when they were discharged. The markers of heart failure were abnormally elevated in the 3 deceased women. Conclusions: Referral should be considered as soon as possible in women with lactic acidosis, hypofibrinogenemia, and hypothermia with AFE.https://www.imrpress.com/journal/CEOG/50/12/10.31083/j.ceog5012255amniotic fluid embolismpregnancyreferralretrospective study |
| spellingShingle | Huiqin Qian Wei Qian Yixiao Wang Sicong Liu Nathan Obore Yuchen Tao You Lv Chengqian Wu Hong Yu Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study Clinical and Experimental Obstetrics & Gynecology amniotic fluid embolism pregnancy referral retrospective study |
| title | Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study |
| title_full | Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study |
| title_fullStr | Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study |
| title_full_unstemmed | Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study |
| title_short | Referral of Pregnant Women with Amniotic Fluid Embolism: A Retrospective, Descriptive Study |
| title_sort | referral of pregnant women with amniotic fluid embolism a retrospective descriptive study |
| topic | amniotic fluid embolism pregnancy referral retrospective study |
| url | https://www.imrpress.com/journal/CEOG/50/12/10.31083/j.ceog5012255 |
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