Radiotherapy-induced bone deterioration is exacerbated in diabetic rats treated with streptozotocin

Radiotherapy-induced bone deterioration is exacerbated in diabetic rats treated with streptozotocin

Following radiotherapy, patients have decreased bone mass and increased risk of fragility fractures. Diabetes mellitus (DM) is also reported to have detrimental effects on bone architecture and quality. However, no clinical or experimental study has systematically characterized the bone phenotype of...

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Bibliographic Details
Main Authors: Maogang Jiang, Yuanjun Ding, Shiwei Xu, Xiaoxia Hao, Yongqing Yang, Erping Luo, Da Jing, Zedong Yan, Jing Cai
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2021-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Radiotherapy
Diabetes mellitus (DM)
Bone loss
Osteoblasts
Osteocytes
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021001200610&tlng=en

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