Research progress of the gut-microbiome-skin axis and psoriasis
Psoriasis is a common chronic recurrent disease in dermatology. IL-23 / Th17 axis plays a critical role in the pathogenesis of psoriasis. In psoriasis patients, the gut-microbiota-skin axis may exit. Gut microbiota dybiosis may be involved in the pathogenesis of psoriasis by inducing the intestinal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2022-12-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/CN/10.3969/j.issn.1674-8468.2022.06.019 |
| _version_ | 1797732613806358528 |
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| author | Zhi XIANG Zhimin HAO Pangen CUI Wenkai ZONG |
| author_facet | Zhi XIANG Zhimin HAO Pangen CUI Wenkai ZONG |
| author_sort | Zhi XIANG |
| collection | DOAJ |
| description | Psoriasis is a common chronic recurrent disease in dermatology. IL-23 / Th17 axis plays a critical role in the pathogenesis of psoriasis. In psoriasis patients, the gut-microbiota-skin axis may exit. Gut microbiota dybiosis may be involved in the pathogenesis of psoriasis by inducing the intestinal mucosal barrier dysfunction, bacterial translocation, inducing excessive activation of Th17, and suppressing the differention of regulatory T cells. We reviewed the recent advances of potential relation between psoriasis and gut microbiota. Probiotics and fecal microbiota transplantation could be novel therapy for psoriasis. |
| first_indexed | 2024-03-12T12:17:01Z |
| format | Article |
| id | doaj.art-c50f73fb290d4820b2f42d3e5763e735 |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-03-12T12:17:01Z |
| publishDate | 2022-12-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-c50f73fb290d4820b2f42d3e5763e7352023-08-30T11:38:54Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682022-12-0129658859210.3969/j.issn.1674-8468.2022.06.019Research progress of the gut-microbiome-skin axis and psoriasisZhi XIANGZhimin HAOPangen CUIWenkai ZONGPsoriasis is a common chronic recurrent disease in dermatology. IL-23 / Th17 axis plays a critical role in the pathogenesis of psoriasis. In psoriasis patients, the gut-microbiota-skin axis may exit. Gut microbiota dybiosis may be involved in the pathogenesis of psoriasis by inducing the intestinal mucosal barrier dysfunction, bacterial translocation, inducing excessive activation of Th17, and suppressing the differention of regulatory T cells. We reviewed the recent advances of potential relation between psoriasis and gut microbiota. Probiotics and fecal microbiota transplantation could be novel therapy for psoriasis.http://pfxbzlx.gdvdc.com/CN/10.3969/j.issn.1674-8468.2022.06.019psoriasisgut microbiomepathogenesis |
| spellingShingle | Zhi XIANG Zhimin HAO Pangen CUI Wenkai ZONG Research progress of the gut-microbiome-skin axis and psoriasis Pifu-xingbing zhenliaoxue zazhi psoriasis gut microbiome pathogenesis |
| title | Research progress of the gut-microbiome-skin axis and psoriasis |
| title_full | Research progress of the gut-microbiome-skin axis and psoriasis |
| title_fullStr | Research progress of the gut-microbiome-skin axis and psoriasis |
| title_full_unstemmed | Research progress of the gut-microbiome-skin axis and psoriasis |
| title_short | Research progress of the gut-microbiome-skin axis and psoriasis |
| title_sort | research progress of the gut microbiome skin axis and psoriasis |
| topic | psoriasis gut microbiome pathogenesis |
| url | http://pfxbzlx.gdvdc.com/CN/10.3969/j.issn.1674-8468.2022.06.019 |
| work_keys_str_mv | AT zhixiang researchprogressofthegutmicrobiomeskinaxisandpsoriasis AT zhiminhao researchprogressofthegutmicrobiomeskinaxisandpsoriasis AT pangencui researchprogressofthegutmicrobiomeskinaxisandpsoriasis AT wenkaizong researchprogressofthegutmicrobiomeskinaxisandpsoriasis |