Summary: | Objective: Nonvariceal
upper gastrointestinal system bleeding (NVUGIB) is a life-threatening condition
that can lead to mortality. It is
important to identify the risk factors in terms of prognosis and mortality in
patients with NVUGIB. In this
study, we assessed the relationship between leukocytosis and neutrophil-to-lymphocyte
ratio and the clinical course in patients with NVUGIB.Materials and Methods:
We
included 156 patients who were diagnosed with NVUGIB between September 2013 and
March 2017 in our clinic. The
relationship between demographic data, endoscopic findings, need for
erythrocyte suspension, length of hospital stay, need for intensive care, need
for surgical intervention and mortality of the patients with the number of
leukocytes and neutrophil-to-lymphocyte ratio (NLR) was investigated.Results: Of the patients, 104 (66,7%) were male, 52 (33,3%) were female, and mean age was
63,8±17,6 years. According to endoscopic findings, the most common cause of the
bleeding was peptic ulcer (77,6%). There was no statistically significant
correlation between leukocyte count and NLR and need for intensive care, need
for surgical intervention and treatment outcome. However, there was a
statistically significant relationship between NLR and length of hospital stay
(p=0,02)
Conclusions: Evaluation
of the patients with NVUGIB timely through their findings detected at admission
and their laboratory results would make a positive contribution to treatment
planning and follow up of the patient. Leukocyte count alone or in combination
with other clinical and laboratory parameters can be a valuable marker in
measuring mortality potential of acutely hospitalized patients. In our study,
we found a significant relationship between NLR and the average length of
hospital stay, which should be encouraged for further studies investigating its
relation with the prognosis of the disease.
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