Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding
Objective: Nonvariceal upper gastrointestinal system bleeding (NVUGIB) is a life-threatening condition that can lead to mortality. It is important to identify the risk factors in terms of prognosis and mortality in patients with NVUGIB. In this study, we assessed the relationship between leukocytosi...
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| Format: | Article |
| Language: | English |
| Published: |
Sakarya University
2018-06-01
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| Series: | Sakarya Tıp Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/497616 |
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| author | Mevlüt Türe Altay Kandemir Mehmet Süle İrfan Yavaşoğlu Adil Coşkun Abdülvahit Yükselen M. Hadi Yaşa |
| author_facet | Mevlüt Türe Altay Kandemir Mehmet Süle İrfan Yavaşoğlu Adil Coşkun Abdülvahit Yükselen M. Hadi Yaşa |
| author_sort | Mevlüt Türe |
| collection | DOAJ |
| description | Objective: Nonvariceal
upper gastrointestinal system bleeding (NVUGIB) is a life-threatening condition
that can lead to mortality. It is
important to identify the risk factors in terms of prognosis and mortality in
patients with NVUGIB. In this
study, we assessed the relationship between leukocytosis and neutrophil-to-lymphocyte
ratio and the clinical course in patients with NVUGIB.Materials and Methods:
We
included 156 patients who were diagnosed with NVUGIB between September 2013 and
March 2017 in our clinic. The
relationship between demographic data, endoscopic findings, need for
erythrocyte suspension, length of hospital stay, need for intensive care, need
for surgical intervention and mortality of the patients with the number of
leukocytes and neutrophil-to-lymphocyte ratio (NLR) was investigated.Results: Of the patients, 104 (66,7%) were male, 52 (33,3%) were female, and mean age was
63,8±17,6 years. According to endoscopic findings, the most common cause of the
bleeding was peptic ulcer (77,6%). There was no statistically significant
correlation between leukocyte count and NLR and need for intensive care, need
for surgical intervention and treatment outcome. However, there was a
statistically significant relationship between NLR and length of hospital stay
(p=0,02)
Conclusions: Evaluation
of the patients with NVUGIB timely through their findings detected at admission
and their laboratory results would make a positive contribution to treatment
planning and follow up of the patient. Leukocyte count alone or in combination
with other clinical and laboratory parameters can be a valuable marker in
measuring mortality potential of acutely hospitalized patients. In our study,
we found a significant relationship between NLR and the average length of
hospital stay, which should be encouraged for further studies investigating its
relation with the prognosis of the disease. |
| first_indexed | 2024-03-08T12:44:44Z |
| format | Article |
| id | doaj.art-c512643af6a547e48addc24a55495294 |
| institution | Directory Open Access Journal |
| issn | 2146-409X |
| language | English |
| last_indexed | 2024-03-08T12:44:44Z |
| publishDate | 2018-06-01 |
| publisher | Sakarya University |
| record_format | Article |
| series | Sakarya Tıp Dergisi |
| spelling | doaj.art-c512643af6a547e48addc24a554952942024-01-21T07:40:11ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2018-06-018232032610.31832/smj.41420228Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System BleedingMevlüt TüreAltay Kandemir0Mehmet Süle1İrfan YavaşoğluAdil Coşkun2Abdülvahit Yükselen3M. Hadi Yaşa4Adnan Menderes Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim DalıBorçka Devlet Hastanesi, Artvin, TürkiyeAdnan Menderes Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim DalıAdnan Menderes Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim DalıAdnan Menderes Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim DalıObjective: Nonvariceal upper gastrointestinal system bleeding (NVUGIB) is a life-threatening condition that can lead to mortality. It is important to identify the risk factors in terms of prognosis and mortality in patients with NVUGIB. In this study, we assessed the relationship between leukocytosis and neutrophil-to-lymphocyte ratio and the clinical course in patients with NVUGIB.Materials and Methods: We included 156 patients who were diagnosed with NVUGIB between September 2013 and March 2017 in our clinic. The relationship between demographic data, endoscopic findings, need for erythrocyte suspension, length of hospital stay, need for intensive care, need for surgical intervention and mortality of the patients with the number of leukocytes and neutrophil-to-lymphocyte ratio (NLR) was investigated.Results: Of the patients, 104 (66,7%) were male, 52 (33,3%) were female, and mean age was 63,8±17,6 years. According to endoscopic findings, the most common cause of the bleeding was peptic ulcer (77,6%). There was no statistically significant correlation between leukocyte count and NLR and need for intensive care, need for surgical intervention and treatment outcome. However, there was a statistically significant relationship between NLR and length of hospital stay (p=0,02) Conclusions: Evaluation of the patients with NVUGIB timely through their findings detected at admission and their laboratory results would make a positive contribution to treatment planning and follow up of the patient. Leukocyte count alone or in combination with other clinical and laboratory parameters can be a valuable marker in measuring mortality potential of acutely hospitalized patients. In our study, we found a significant relationship between NLR and the average length of hospital stay, which should be encouraged for further studies investigating its relation with the prognosis of the disease.https://dergipark.org.tr/tr/download/article-file/497616nonvariceal upper gastrointestinal bleedingleukocytosisneutrophil-to-lymphocyte rationonvarisial üst gastrointestinal sistem kanamasılökositoznötrofil-lenfosit oranı |
| spellingShingle | Mevlüt Türe Altay Kandemir Mehmet Süle İrfan Yavaşoğlu Adil Coşkun Abdülvahit Yükselen M. Hadi Yaşa Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding Sakarya Tıp Dergisi nonvariceal upper gastrointestinal bleeding leukocytosis neutrophil-to-lymphocyte ratio nonvarisial üst gastrointestinal sistem kanaması lökositoz nötrofil-lenfosit oranı |
| title | Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding |
| title_full | Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding |
| title_fullStr | Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding |
| title_full_unstemmed | Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding |
| title_short | Assessment of the Relationship Between Leukocyte Count and Neutrophil-to-Lymphocyte Ratio and Clinical Course in Non-Variceal Upper Gastrointestinal System Bleeding |
| title_sort | assessment of the relationship between leukocyte count and neutrophil to lymphocyte ratio and clinical course in non variceal upper gastrointestinal system bleeding |
| topic | nonvariceal upper gastrointestinal bleeding leukocytosis neutrophil-to-lymphocyte ratio nonvarisial üst gastrointestinal sistem kanaması lökositoz nötrofil-lenfosit oranı |
| url | https://dergipark.org.tr/tr/download/article-file/497616 |
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