Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia.
Objective: To determine the value of random urinary protein to creatinine ratio (UPCR) for diagnosis of proteinuria in pregnant women with preeclampsia. Preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. So, early diagnosis of preeclampsia is...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2013-06-01
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| Series: | Journal of Family and Reproductive Health |
| Subjects: | |
| Online Access: | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/280 |
| _version_ | 1818882883363799040 |
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| author | Sakineh Moaid Mohseni Nafiseh Moez Mohammad Mehdi Naghizadeh Maryam Abbasi Zohreh Khodashenas |
| author_facet | Sakineh Moaid Mohseni Nafiseh Moez Mohammad Mehdi Naghizadeh Maryam Abbasi Zohreh Khodashenas |
| author_sort | Sakineh Moaid Mohseni |
| collection | DOAJ |
| description | Objective: To determine the value of random urinary protein to creatinine ratio (UPCR) for diagnosis of proteinuria in pregnant women with preeclampsia. Preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. So, early diagnosis of preeclampsia is very important.
Materials and methods: In this cross-sectional study 66 pregnant women suspected preeclampsia at ≥24 week of gestational age and BP ≥ 140/90 mm/Hg were checked by two urine samples of 10am and 4pm to determine random UPCR, as well as a 24-hour urine sample to evaluate 24-hour protein excretion.
Results: The result revealed that 74.2% of the studied population had significant proteinuria. There was a correlation between UPCR and 24-hour urine protein excretion. Pearson's correlation coefficient was 0.502 at 10am and 0.428 at 4pm. The best cutoff for the random urine protein to creatinine ratio at 10am was 0.470 with sensitivity and specificity equal to 87.5% and 84.2%, respectively. The best cutoff for the random UPCR at 4pm was 0.595 with sensitivity and specificity equal to 91.7% and 94.7%, respectively.
Conclusion: Result of 24-hour urine collection showing random UPCR is considered as an appropriate situated method for emergency time. |
| first_indexed | 2024-12-19T15:24:50Z |
| format | Article |
| id | doaj.art-c51615bb278b470e830aacd5eaa64027 |
| institution | Directory Open Access Journal |
| issn | 1735-8949 1735-9392 |
| language | English |
| last_indexed | 2024-12-19T15:24:50Z |
| publishDate | 2013-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Family and Reproductive Health |
| spelling | doaj.art-c51615bb278b470e830aacd5eaa640272022-12-21T20:15:55ZengTehran University of Medical SciencesJournal of Family and Reproductive Health1735-89491735-93922013-06-0172275Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia.Sakineh Moaid Mohseni0Nafiseh Moez1Mohammad Mehdi Naghizadeh2Maryam Abbasi3Zohreh Khodashenas4Department of Gynecology and Obstetrics, Shahed University of Medical Science Tehran, Iran.Shahed University of Medical Science, Tehran, Iran.Department of Biostatistics, Fasa University of Medical Sciences, Fasa, Iran.Shahed University of Medical Science, Tehran, Iran.Shahed University of Medical Science, Tehran, Iran.Objective: To determine the value of random urinary protein to creatinine ratio (UPCR) for diagnosis of proteinuria in pregnant women with preeclampsia. Preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. So, early diagnosis of preeclampsia is very important. Materials and methods: In this cross-sectional study 66 pregnant women suspected preeclampsia at ≥24 week of gestational age and BP ≥ 140/90 mm/Hg were checked by two urine samples of 10am and 4pm to determine random UPCR, as well as a 24-hour urine sample to evaluate 24-hour protein excretion. Results: The result revealed that 74.2% of the studied population had significant proteinuria. There was a correlation between UPCR and 24-hour urine protein excretion. Pearson's correlation coefficient was 0.502 at 10am and 0.428 at 4pm. The best cutoff for the random urine protein to creatinine ratio at 10am was 0.470 with sensitivity and specificity equal to 87.5% and 84.2%, respectively. The best cutoff for the random UPCR at 4pm was 0.595 with sensitivity and specificity equal to 91.7% and 94.7%, respectively. Conclusion: Result of 24-hour urine collection showing random UPCR is considered as an appropriate situated method for emergency time.https://jfrh.tums.ac.ir/index.php/jfrh/article/view/280PreeclampsiaPregnancyProtein to creatinine ratioProteinuria |
| spellingShingle | Sakineh Moaid Mohseni Nafiseh Moez Mohammad Mehdi Naghizadeh Maryam Abbasi Zohreh Khodashenas Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. Journal of Family and Reproductive Health Preeclampsia Pregnancy Protein to creatinine ratio Proteinuria |
| title | Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. |
| title_full | Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. |
| title_fullStr | Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. |
| title_full_unstemmed | Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. |
| title_short | Correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia. |
| title_sort | correlation of random urinary protein to creatinine ratio in 24 hour urine samples of pregnant women with preeclampsia |
| topic | Preeclampsia Pregnancy Protein to creatinine ratio Proteinuria |
| url | https://jfrh.tums.ac.ir/index.php/jfrh/article/view/280 |
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