The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

Mimivirus is the prototype of the Mimiviridae family of giant dsDNA viruses. Little is known about the organization of the 1.2 Mb genome inside the membrane-limited nucleoid filling the ~0.5 µm icosahedral capsids. Cryo-electron microscopy, cryo-electron tomography, and proteomics revealed that it i...

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Bibliographic Details
Main Authors: Alejandro Villalta, Alain Schmitt, Leandro F Estrozi, Emmanuelle RJ Quemin, Jean-Marie Alempic, Audrey Lartigue, Vojtěch Pražák, Lucid Belmudes, Daven Vasishtan, Agathe MG Colmant, Flora A Honoré, Yohann Couté, Kay Grünewald, Chantal Abergel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
mimivirus
giant virus
viral dsDNA organization
cryo-EM
cryo-ET
proteomics
Online Access:https://elifesciences.org/articles/77607

Internet

https://elifesciences.org/articles/77607

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