Y-Chromosome Genetic Analysis of Modern Polish Population
The study presents a full analysis of the Y-chromosome variability of the modern male Polish population. It is the first study of the Polish population to be conducted with such a large set of data (2,705 individuals), which includes genetic information from inhabitants of all voivodeships, i.e., th...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-10-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2020.567309/full |
| _version_ | 1828889221827395584 |
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| author | Łukasz Grochowalski Justyna Jarczak Justyna Jarczak Maria Urbanowicz Marcin Słomka Marcin Słomka Maria Szargut Maria Szargut Paulina Borówka Marta Sobalska-Kwapis Marta Sobalska-Kwapis Błażej Marciniak Błażej Marciniak Andrzej Ossowski Andrzej Ossowski Wiesław Lorkiewicz Dominik Strapagiel Dominik Strapagiel |
| author_facet | Łukasz Grochowalski Justyna Jarczak Justyna Jarczak Maria Urbanowicz Marcin Słomka Marcin Słomka Maria Szargut Maria Szargut Paulina Borówka Marta Sobalska-Kwapis Marta Sobalska-Kwapis Błażej Marciniak Błażej Marciniak Andrzej Ossowski Andrzej Ossowski Wiesław Lorkiewicz Dominik Strapagiel Dominik Strapagiel |
| author_sort | Łukasz Grochowalski |
| collection | DOAJ |
| description | The study presents a full analysis of the Y-chromosome variability of the modern male Polish population. It is the first study of the Polish population to be conducted with such a large set of data (2,705 individuals), which includes genetic information from inhabitants of all voivodeships, i.e., the first administrative level, in the country and the vast majority of its counties, i.e., the second level. In addition, the available data were divided into clusters corresponding to more natural geographic regions. Genetic analysis included the estimation of FST distances, the visualization with the use of multidimensional scaling plots and analysis of molecular variance. Y-chromosome binary haplogroups were classified and visualized with the use of interpolation maps. Results showed that the level of differentiation within Polish population is quite low, but some differences were indicated. It was confirmed that the Polish population is characterized by a high degree of homogeneity, with only slight genetic differences being observed at the regional level. The use of regional clustering as an alternative to counties and voivodeships provided a more detailed view of the genetic structure of the population. Those regional differences identified in the present study highlighted the need for additional division of the population by cultural and ethnic criteria in such studies rather than just by geographical or administrative regionalization. |
| first_indexed | 2024-12-13T12:37:21Z |
| format | Article |
| id | doaj.art-c518cbbbc3fc4e9e8983ab608aa6c91f |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-12-13T12:37:21Z |
| publishDate | 2020-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-c518cbbbc3fc4e9e8983ab608aa6c91f2022-12-21T23:45:47ZengFrontiers Media S.A.Frontiers in Genetics1664-80212020-10-011110.3389/fgene.2020.567309567309Y-Chromosome Genetic Analysis of Modern Polish PopulationŁukasz Grochowalski0Justyna Jarczak1Justyna Jarczak2Maria Urbanowicz3Marcin Słomka4Marcin Słomka5Maria Szargut6Maria Szargut7Paulina Borówka8Marta Sobalska-Kwapis9Marta Sobalska-Kwapis10Błażej Marciniak11Błażej Marciniak12Andrzej Ossowski13Andrzej Ossowski14Wiesław Lorkiewicz15Dominik Strapagiel16Dominik Strapagiel17Biobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBBMRI.pl Consortium, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBBMRI.pl Consortium, Łódź, PolandDepartment of Forensic Genetics, Pomeranian Medical University in Szczecin, Szczecin, PolandThe Polish Genetic Database of Totalitarianism Victims, Szczecin, PolandDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBBMRI.pl Consortium, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBBMRI.pl Consortium, Łódź, PolandDepartment of Forensic Genetics, Pomeranian Medical University in Szczecin, Szczecin, PolandThe Polish Genetic Database of Totalitarianism Victims, Szczecin, PolandDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Łódź, PolandBBMRI.pl Consortium, Łódź, PolandThe study presents a full analysis of the Y-chromosome variability of the modern male Polish population. It is the first study of the Polish population to be conducted with such a large set of data (2,705 individuals), which includes genetic information from inhabitants of all voivodeships, i.e., the first administrative level, in the country and the vast majority of its counties, i.e., the second level. In addition, the available data were divided into clusters corresponding to more natural geographic regions. Genetic analysis included the estimation of FST distances, the visualization with the use of multidimensional scaling plots and analysis of molecular variance. Y-chromosome binary haplogroups were classified and visualized with the use of interpolation maps. Results showed that the level of differentiation within Polish population is quite low, but some differences were indicated. It was confirmed that the Polish population is characterized by a high degree of homogeneity, with only slight genetic differences being observed at the regional level. The use of regional clustering as an alternative to counties and voivodeships provided a more detailed view of the genetic structure of the population. Those regional differences identified in the present study highlighted the need for additional division of the population by cultural and ethnic criteria in such studies rather than just by geographical or administrative regionalization.https://www.frontiersin.org/articles/10.3389/fgene.2020.567309/fullY-chromosomehaplogroupsPolish populationregions of Polandmicroarray analysisSNPs |
| spellingShingle | Łukasz Grochowalski Justyna Jarczak Justyna Jarczak Maria Urbanowicz Marcin Słomka Marcin Słomka Maria Szargut Maria Szargut Paulina Borówka Marta Sobalska-Kwapis Marta Sobalska-Kwapis Błażej Marciniak Błażej Marciniak Andrzej Ossowski Andrzej Ossowski Wiesław Lorkiewicz Dominik Strapagiel Dominik Strapagiel Y-Chromosome Genetic Analysis of Modern Polish Population Frontiers in Genetics Y-chromosome haplogroups Polish population regions of Poland microarray analysis SNPs |
| title | Y-Chromosome Genetic Analysis of Modern Polish Population |
| title_full | Y-Chromosome Genetic Analysis of Modern Polish Population |
| title_fullStr | Y-Chromosome Genetic Analysis of Modern Polish Population |
| title_full_unstemmed | Y-Chromosome Genetic Analysis of Modern Polish Population |
| title_short | Y-Chromosome Genetic Analysis of Modern Polish Population |
| title_sort | y chromosome genetic analysis of modern polish population |
| topic | Y-chromosome haplogroups Polish population regions of Poland microarray analysis SNPs |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2020.567309/full |
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