Airway host-microbiome interactions in chronic obstructive pulmonary disease

Airway host-microbiome interactions in chronic obstructive pulmonary disease

Abstract Background Little is known about the interactions between the lung microbiome and host response in chronic obstructive pulmonary disease (COPD). Methods We performed a longitudinal 16S ribosomal RNA gene-based microbiome survey on 101 sputum samples from 16 healthy subjects and 43 COPD pati...

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Bibliographic Details
Main Authors: Zhang Wang, Barbara Maschera, Simon Lea, Umme Kolsum, David Michalovich, Stephanie Van Horn, Christopher Traini, James R. Brown, Edith M. Hessel, Dave Singh
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
COPD
Microbiome
Exacerbations
Clinical study
Transcriptome
Online Access:http://link.springer.com/article/10.1186/s12931-019-1085-z

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