Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology

Microfluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to impact biology and medicine. Microfluidic devices...

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Main Authors: Se Hwan Hwang, Alan M. Gonzalez-Suarez, Gulnaz Stybayeva, Alexander Revzin
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2021-02-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Online Access:http://www.e-ceo.org/upload/pdf/ceo-2020-00626.pdf
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author Se Hwan Hwang
Alan M. Gonzalez-Suarez
Gulnaz Stybayeva
Alexander Revzin
author_facet Se Hwan Hwang
Alan M. Gonzalez-Suarez
Gulnaz Stybayeva
Alexander Revzin
author_sort Se Hwan Hwang
collection DOAJ
description Microfluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to impact biology and medicine. Microfluidic devices populated with human cells have the potential to mimic the physiological functions of tissues and organs in a three-dimensional microenvironment and enable the study of mechanisms of human diseases, drug discovery and the practice of personalized medicine. In the field of otorhinolaryngology, various types of microfluidic systems have already been introduced to study organ physiology, diagnose diseases, and evaluate therapeutic efficacy. Therefore, microfluidic technologies can be implemented at all levels of otorhinolaryngology. This review is intended to promote understanding of microfluidic properties and introduce the recent literature on application of microfluidic-related devices in the field of otorhinolaryngology.
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spelling doaj.art-c51b018853834a0294e4dfff58d96f0b2022-12-21T19:41:12ZengKorean Society of Otorhinolaryngology-Head and Neck SurgeryClinical and Experimental Otorhinolaryngology1976-87102005-07202021-02-01141294210.21053/ceo.2020.00626733Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of OtorhinolaryngologySe Hwan Hwang0Alan M. Gonzalez-Suarez1Gulnaz Stybayeva2Alexander Revzin3 Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USAMicrofluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to impact biology and medicine. Microfluidic devices populated with human cells have the potential to mimic the physiological functions of tissues and organs in a three-dimensional microenvironment and enable the study of mechanisms of human diseases, drug discovery and the practice of personalized medicine. In the field of otorhinolaryngology, various types of microfluidic systems have already been introduced to study organ physiology, diagnose diseases, and evaluate therapeutic efficacy. Therefore, microfluidic technologies can be implemented at all levels of otorhinolaryngology. This review is intended to promote understanding of microfluidic properties and introduce the recent literature on application of microfluidic-related devices in the field of otorhinolaryngology.http://www.e-ceo.org/upload/pdf/ceo-2020-00626.pdfmicrofluidicsorganoidsin vitro diagnosticsorgan-on-a-chipotolaryngology
spellingShingle Se Hwan Hwang
Alan M. Gonzalez-Suarez
Gulnaz Stybayeva
Alexander Revzin
Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
Clinical and Experimental Otorhinolaryngology
microfluidics
organoids
in vitro diagnostics
organ-on-a-chip
otolaryngology
title Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
title_full Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
title_fullStr Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
title_full_unstemmed Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
title_short Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology
title_sort prospects and opportunities for microsystems and microfluidic devices in the field of otorhinolaryngology
topic microfluidics
organoids
in vitro diagnostics
organ-on-a-chip
otolaryngology
url http://www.e-ceo.org/upload/pdf/ceo-2020-00626.pdf
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