Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis
Regulation of oriented cell divisions during development is important to position daughter cells and build a structured and functional tissue. Here the authors show that Annexin A1 is a key polarity protein that regulates planar orientation of the cell division axis to guide mammary epithelial morph...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-35881-x |
| _version_ | 1797952442678116352 |
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| author | Maria Fankhaenel Farahnaz S. Golestan Hashemi Larissa Mourao Emily Lucas Manal M. Hosawi Paul Skipp Xavier Morin Colinda L.G.J. Scheele Salah Elias |
| author_facet | Maria Fankhaenel Farahnaz S. Golestan Hashemi Larissa Mourao Emily Lucas Manal M. Hosawi Paul Skipp Xavier Morin Colinda L.G.J. Scheele Salah Elias |
| author_sort | Maria Fankhaenel |
| collection | DOAJ |
| description | Regulation of oriented cell divisions during development is important to position daughter cells and build a structured and functional tissue. Here the authors show that Annexin A1 is a key polarity protein that regulates planar orientation of the cell division axis to guide mammary epithelial morphogenesis. |
| first_indexed | 2024-04-10T22:47:31Z |
| format | Article |
| id | doaj.art-c51bf70fb3914b9fa2bd6c3a06c9b142 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-10T22:47:31Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-c51bf70fb3914b9fa2bd6c3a06c9b1422023-01-15T12:16:24ZengNature PortfolioNature Communications2041-17232023-01-0114112010.1038/s41467-023-35881-xAnnexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesisMaria Fankhaenel0Farahnaz S. Golestan Hashemi1Larissa Mourao2Emily Lucas3Manal M. Hosawi4Paul Skipp5Xavier Morin6Colinda L.G.J. Scheele7Salah Elias8School of Biological Sciences, University of SouthamptonSchool of Biological Sciences, University of SouthamptonVIB-KULeuven Center for Cancer Biology, Herestraat 49School of Biological Sciences, University of SouthamptonSchool of Biological Sciences, University of SouthamptonSchool of Biological Sciences, University of SouthamptonEcole Normale Supérieure, CNRS, Inserm, Institut de Biologie de l’Ecole Normale Supérieure (IBENS), PSL Research UniversityVIB-KULeuven Center for Cancer Biology, Herestraat 49School of Biological Sciences, University of SouthamptonRegulation of oriented cell divisions during development is important to position daughter cells and build a structured and functional tissue. Here the authors show that Annexin A1 is a key polarity protein that regulates planar orientation of the cell division axis to guide mammary epithelial morphogenesis.https://doi.org/10.1038/s41467-023-35881-x |
| spellingShingle | Maria Fankhaenel Farahnaz S. Golestan Hashemi Larissa Mourao Emily Lucas Manal M. Hosawi Paul Skipp Xavier Morin Colinda L.G.J. Scheele Salah Elias Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis Nature Communications |
| title | Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| title_full | Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| title_fullStr | Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| title_full_unstemmed | Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| title_short | Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| title_sort | annexin a1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis |
| url | https://doi.org/10.1038/s41467-023-35881-x |
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