Endogenous Retroviruses Walk a Fine Line between Priming and Silencing
Endogenous retroviruses (ERVs) in mammals are closely related to infectious retroviruses and utilize host tRNAs as a primer for reverse transcription and replication, a hallmark of long terminal repeat (LTR) retroelements. Their dependency on tRNA makes these elements vulnerable to targeting by smal...
Main Authors: | Harrison Cullen, Andrea J. Schorn |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/12/8/792 |
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