Nephropathic Cystinosis: Pathogenic Roles of Inflammation and Potential for New Therapies

Nephropathic Cystinosis: Pathogenic Roles of Inflammation and Potential for New Therapies

The activation of several inflammatory pathways has recently been documented in patients and different cellular and animal models of nephropathic cystinosis. Upregulated inflammatory signals interact with many pathogenic aspects of the disease, such as enhanced oxidative stress, abnormal autophagy,...

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Bibliographic Details
Main Authors: Mohamed A. Elmonem, Koenraad R. P. Veys, Giusi Prencipe
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
macrophages
inflammasome
proximal tubular cells
endocytosis
autophagy
apoptosis
Online Access:https://www.mdpi.com/2073-4409/11/2/190

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