Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation

The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement. The role of high doses of glucocorticoids and coagulation disorder...

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Main Authors: F. A. Cheldieva, I. G. Kushnareva, V. V. Babak, A. E. Khramov, T. M. Reshetnyak
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2021-04-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1125
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author F. A. Cheldieva
I. G. Kushnareva
V. V. Babak
A. E. Khramov
T. M. Reshetnyak
author_facet F. A. Cheldieva
I. G. Kushnareva
V. V. Babak
A. E. Khramov
T. M. Reshetnyak
author_sort F. A. Cheldieva
collection DOAJ
description The article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement. The role of high doses of glucocorticoids and coagulation disorders, in particular the homozygous mutation in factor V (Leiden) gene, in the development of ABN is discussed.
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spelling doaj.art-c5243fa7fa044ac897c65a31876a58032023-03-13T08:39:28ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-04-01152697610.14412/1996-7012-2021-2-69-762346Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observationF. A. Cheldieva0I. G. Kushnareva1V. V. Babak2A. E. Khramov3T. M. Reshetnyak4ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииThe article provides a description of the systemic lupus erythematosus patient with multiple avascular bone necrosis (ABN), homozygous mutation in clotting factor V (Leiden) gene, who successfully underwent the total hip replacement. The role of high doses of glucocorticoids and coagulation disorders, in particular the homozygous mutation in factor V (Leiden) gene, in the development of ABN is discussed.https://mrj.ima-press.net/mrj/article/view/1125системная красная волчанкааваскулярный некроз костеймутация leidenглюкокортикоиды
spellingShingle F. A. Cheldieva
I. G. Kushnareva
V. V. Babak
A. E. Khramov
T. M. Reshetnyak
Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
Современная ревматология
системная красная волчанка
аваскулярный некроз костей
мутация leiden
глюкокортикоиды
title Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
title_full Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
title_fullStr Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
title_full_unstemmed Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
title_short Avascular necrosis in systemic lupus erythematosus: total hip replacement in a patient with mutation in clotting factor V (Leiden) gene, clinical observation
title_sort avascular necrosis in systemic lupus erythematosus total hip replacement in a patient with mutation in clotting factor v leiden gene clinical observation
topic системная красная волчанка
аваскулярный некроз костей
мутация leiden
глюкокортикоиды
url https://mrj.ima-press.net/mrj/article/view/1125
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