Split selectable markers

Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Nathaniel Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert Wu Cheng
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2019-10-01
Σειρά:Nature Communications
Διαθέσιμο Online:https://doi.org/10.1038/s41467-019-12891-2
Περιγραφή
Περίληψη:Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.
ISSN:2041-1723