Split selectable markers

Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.

Bibliografiska uppgifter
Huvudupphovsmän: Nathaniel Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert Wu Cheng
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2019-10-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-019-12891-2
Beskrivning
Sammanfattning:Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.
ISSN:2041-1723