Relationship between Multiple Sclerosis-Associated <i>IL2RA</i> Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls

Relationship between Multiple Sclerosis-Associated <i>IL2RA</i> Risk Allele Variants and Circulating T Cell Phenotypes in Healthy Genotype-Selected Controls

Single nucleotide polymorphisms (SNPs) in or near the <i>IL2RA</i> gene, that encodes the interleukin-2 (IL-2) receptor &#945; (CD25), are associated with increased risk of immune-mediated diseases including multiple sclerosis (MS). We investigated how the MS-associated <i>IL2R...

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Bibliographic Details
Main Authors: Sophie Buhelt, Helle Bach Søndergaard, Annette Oturai, Henrik Ullum, Marina Rode von Essen, Finn Sellebjerg
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
<i>IL2RA</i>
CD25
multiple sclerosis
rs2104286
rs11256593
interleukin-2 receptor
Online Access:https://www.mdpi.com/2073-4409/8/6/634

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