Shear-sensitive factors in therapeutic targets for atherosclerosis

Clinical and basic research evidence suggests a critical role of local hemodynamic microenvironments in atherogenesis. Disturbed flow with a low and reciprocating shear stress in arterial branches and curvatures induces endothelial dysregulation and damage, leading to atherosclerosis. In contrast, l...

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Bibliographic Details
Main Author: ZHAO Chuan-rong, ZHOU Jing
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-03-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-378.pdf