What Do We Know about Spondylodiscitis in Children? A Retrospective Study
Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a thi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/8/1103 |
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| author | Ayla Yagdiran Charlotte Meyer-Schwickerath Raphael Wolpers Christina Otto-Lambertz Katrin Mehler Andre Oberthür Nikolaus Kernich Peer Eysel Norma Jung Kourosh Zarghooni |
| author_facet | Ayla Yagdiran Charlotte Meyer-Schwickerath Raphael Wolpers Christina Otto-Lambertz Katrin Mehler Andre Oberthür Nikolaus Kernich Peer Eysel Norma Jung Kourosh Zarghooni |
| author_sort | Ayla Yagdiran |
| collection | DOAJ |
| description | Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a third-level hospital (2009–2019) in PSD and compare these with adult spondylodiscitis (ASD). Of a total of 10 PSD patients, most of the infants presented with unspecific pain such as hip pain or a limping, misleading an adequate diagnosis of spine origin. Eight patients could be treated conservatively whereas surgery was performed in two cases with one case of tuberculous PSD (tPSD). The causative agent was detected in three of the patients. The diagnosis of PSD is often difficult since clinical symptoms are unspecific and causative pathogens often remain undetected. Nevertheless, empirical anti-infective therapy also seems to be effective. Based on recent studies, clinicians should be encouraged to keep the duration of anti-infective therapy in children short. Since comorbidities are not presented in PSD it is unclear which children suffer from PSD; thus, studies are necessary to identify predisposing factors for PSD. In our study, PSD differs from ASD in diagnostic and especially in therapeutic aspects. Therefore, specific guidelines for PSD would be desirable. |
| first_indexed | 2024-03-09T04:36:13Z |
| format | Article |
| id | doaj.art-c529454b0ea34e21a968def03ec0e68c |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T04:36:13Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-c529454b0ea34e21a968def03ec0e68c2023-12-03T13:27:58ZengMDPI AGChildren2227-90672022-07-0198110310.3390/children9081103What Do We Know about Spondylodiscitis in Children? A Retrospective StudyAyla Yagdiran0Charlotte Meyer-Schwickerath1Raphael Wolpers2Christina Otto-Lambertz3Katrin Mehler4Andre Oberthür5Nikolaus Kernich6Peer Eysel7Norma Jung8Kourosh Zarghooni9Department of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated Oncology, University of Cologne, 50937 Cologne, GermanyDepartment of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment of Pediatrics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment of Pediatrics, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyDepartment I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated Oncology, University of Cologne, 50937 Cologne, GermanyDepartment of Orthopedic and Trauma Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, GermanyPediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a third-level hospital (2009–2019) in PSD and compare these with adult spondylodiscitis (ASD). Of a total of 10 PSD patients, most of the infants presented with unspecific pain such as hip pain or a limping, misleading an adequate diagnosis of spine origin. Eight patients could be treated conservatively whereas surgery was performed in two cases with one case of tuberculous PSD (tPSD). The causative agent was detected in three of the patients. The diagnosis of PSD is often difficult since clinical symptoms are unspecific and causative pathogens often remain undetected. Nevertheless, empirical anti-infective therapy also seems to be effective. Based on recent studies, clinicians should be encouraged to keep the duration of anti-infective therapy in children short. Since comorbidities are not presented in PSD it is unclear which children suffer from PSD; thus, studies are necessary to identify predisposing factors for PSD. In our study, PSD differs from ASD in diagnostic and especially in therapeutic aspects. Therefore, specific guidelines for PSD would be desirable.https://www.mdpi.com/2227-9067/9/8/1103pediatric spondylodiscitisclinical coursediagnosistreatmentpredicting factors |
| spellingShingle | Ayla Yagdiran Charlotte Meyer-Schwickerath Raphael Wolpers Christina Otto-Lambertz Katrin Mehler Andre Oberthür Nikolaus Kernich Peer Eysel Norma Jung Kourosh Zarghooni What Do We Know about Spondylodiscitis in Children? A Retrospective Study Children pediatric spondylodiscitis clinical course diagnosis treatment predicting factors |
| title | What Do We Know about Spondylodiscitis in Children? A Retrospective Study |
| title_full | What Do We Know about Spondylodiscitis in Children? A Retrospective Study |
| title_fullStr | What Do We Know about Spondylodiscitis in Children? A Retrospective Study |
| title_full_unstemmed | What Do We Know about Spondylodiscitis in Children? A Retrospective Study |
| title_short | What Do We Know about Spondylodiscitis in Children? A Retrospective Study |
| title_sort | what do we know about spondylodiscitis in children a retrospective study |
| topic | pediatric spondylodiscitis clinical course diagnosis treatment predicting factors |
| url | https://www.mdpi.com/2227-9067/9/8/1103 |
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