Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)

<i>Cannabis sativa</i> L. is a plant that humankind has been using for millennia. The basis of its widespread utilization is its adaptability to so many different climatic conditions, with easy cultivability in numerous diverse environments. Because of its variegate phytochemistry, <i...

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Main Authors: Laura Siracusa, Giuseppe Ruberto, Luigia Cristino
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/8/3387
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author Laura Siracusa
Giuseppe Ruberto
Luigia Cristino
author_facet Laura Siracusa
Giuseppe Ruberto
Luigia Cristino
author_sort Laura Siracusa
collection DOAJ
description <i>Cannabis sativa</i> L. is a plant that humankind has been using for millennia. The basis of its widespread utilization is its adaptability to so many different climatic conditions, with easy cultivability in numerous diverse environments. Because of its variegate phytochemistry, <i>C. sativa</i> has been used in many sectors, although the discovery of the presence in the plant of several psychotropic substances (e.g., Δ<sup>9</sup>-tetrahydrocannabinol, THC) caused a drastic reduction of its cultivation and use together with its official ban from pharmacopeias. Fortunately, the discovery of <i>Cannabis</i> varieties with low content of THC as well as the biotechnological development of new clones rich in many phytochemical components endorsed with peculiar and many important bioactivities has demanded the reassessment of these species, the study and use of which are currently experiencing new and important developments. In this review we focus our attention on the phytochemistry, new matrices, suitable agronomic techniques, and new biological activities developed in the five last years.
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spelling doaj.art-c52a034de6a948d394178906a49923492023-11-17T20:38:16ZengMDPI AGMolecules1420-30492023-04-01288338710.3390/molecules28083387Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)Laura Siracusa0Giuseppe Ruberto1Luigia Cristino2Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Paolo Gaifami, 18, 95126 Catania, CT, ItalyIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Paolo Gaifami, 18, 95126 Catania, CT, ItalyIstituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078 Pozzuoli, NA, Italy<i>Cannabis sativa</i> L. is a plant that humankind has been using for millennia. The basis of its widespread utilization is its adaptability to so many different climatic conditions, with easy cultivability in numerous diverse environments. Because of its variegate phytochemistry, <i>C. sativa</i> has been used in many sectors, although the discovery of the presence in the plant of several psychotropic substances (e.g., Δ<sup>9</sup>-tetrahydrocannabinol, THC) caused a drastic reduction of its cultivation and use together with its official ban from pharmacopeias. Fortunately, the discovery of <i>Cannabis</i> varieties with low content of THC as well as the biotechnological development of new clones rich in many phytochemical components endorsed with peculiar and many important bioactivities has demanded the reassessment of these species, the study and use of which are currently experiencing new and important developments. In this review we focus our attention on the phytochemistry, new matrices, suitable agronomic techniques, and new biological activities developed in the five last years.https://www.mdpi.com/1420-3049/28/8/3387<i>Cannabis sativa</i> L.secondary metabolismcannabinoidsminor compoundsalternative <i>Cannabis</i> matricescontrolled growth
spellingShingle Laura Siracusa
Giuseppe Ruberto
Luigia Cristino
Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
Molecules
<i>Cannabis sativa</i> L.
secondary metabolism
cannabinoids
minor compounds
alternative <i>Cannabis</i> matrices
controlled growth
title Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
title_full Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
title_fullStr Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
title_full_unstemmed Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
title_short Recent Research on <i>Cannabis sativa</i> L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)
title_sort recent research on i cannabis sativa i l phytochemistry new matrices cultivation techniques and recent updates on its brain related effects 2018 2023
topic <i>Cannabis sativa</i> L.
secondary metabolism
cannabinoids
minor compounds
alternative <i>Cannabis</i> matrices
controlled growth
url https://www.mdpi.com/1420-3049/28/8/3387
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