Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates

Aim:The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection of donor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in the d...

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Bibliographic Details
Main Authors: Bedriye KOYUNCU SÖKMEN, Tolga ŞAHİN, Alihan ORAL, Erdem KOÇAK
Format: Article
Language:English
Published: Galenos Yayincilik 2021-08-01
Series:Namık Kemal Tıp Dergisi
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Online Access: http://namikkemalmedj.com/archives/archive-detail/article-preview/comparison-of-biopsy-computed-tomography-and-magne/48565
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Summary:Aim:The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection of donor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in the detection of HS in live liver donor candidates.Materials and Methods:Two hundred twenty-six healthy individuals who were admitted to Demiroğlu Bilim University as donor candidates for LT were included in the study. Demographic, histopathological, laboratory and imaging findings of the donors were retrospectively reviewed. Computed tomography (CT) and magnetic resonance imaging (MRI) scans of the donors were retrospectively reevaluated and liver fat measurements were recorded.Results:39% (88) of the patients were female and 61% (138) were male. In the study population, the mean age was 34.3±8.7 years, the mean weight was 78.0±12.6 kg, the mean height was 169.1±9.6 cm, and the mean body mass index was 27.2±4.0. 42% of donors had <5% HS, and 58% of donors had >5% HS in liver biopsy. Both CT and MRI showed significant correlations with biopsy in HS detection (p<0.05).Conclusion:In our study, it was found that MRI correlated with biopsy as much as CT and could be used easily in the detection of HS. The use of MRI in liver donors may be more appropriate for donor health prior to transplantation.
ISSN:2587-0262