Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates
Aim:The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection of donor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in the d...
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| Format: | Article |
| Language: | English |
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Galenos Yayincilik
2021-08-01
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| Series: | Namık Kemal Tıp Dergisi |
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http://namikkemalmedj.com/archives/archive-detail/article-preview/comparison-of-biopsy-computed-tomography-and-magne/48565
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| _version_ | 1797912669247766528 |
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| author | Bedriye KOYUNCU SÖKMEN Tolga ŞAHİN Alihan ORAL Erdem KOÇAK |
| author_facet | Bedriye KOYUNCU SÖKMEN Tolga ŞAHİN Alihan ORAL Erdem KOÇAK |
| author_sort | Bedriye KOYUNCU SÖKMEN |
| collection | DOAJ |
| description | Aim:The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection of donor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in the detection of HS in live liver donor candidates.Materials and Methods:Two hundred twenty-six healthy individuals who were admitted to Demiroğlu Bilim University as donor candidates for LT were included in the study. Demographic, histopathological, laboratory and imaging findings of the donors were retrospectively reviewed. Computed tomography (CT) and magnetic resonance imaging (MRI) scans of the donors were retrospectively reevaluated and liver fat measurements were recorded.Results:39% (88) of the patients were female and 61% (138) were male. In the study population, the mean age was 34.3±8.7 years, the mean weight was 78.0±12.6 kg, the mean height was 169.1±9.6 cm, and the mean body mass index was 27.2±4.0. 42% of donors had <5% HS, and 58% of donors had >5% HS in liver biopsy. Both CT and MRI showed significant correlations with biopsy in HS detection (p<0.05).Conclusion:In our study, it was found that MRI correlated with biopsy as much as CT and could be used easily in the detection of HS. The use of MRI in liver donors may be more appropriate for donor health prior to transplantation. |
| first_indexed | 2024-04-10T11:59:30Z |
| format | Article |
| id | doaj.art-c52bfa592dc347d081f8732c4a5ef393 |
| institution | Directory Open Access Journal |
| issn | 2587-0262 |
| language | English |
| last_indexed | 2024-04-10T11:59:30Z |
| publishDate | 2021-08-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Namık Kemal Tıp Dergisi |
| spelling | doaj.art-c52bfa592dc347d081f8732c4a5ef3932023-02-15T16:16:41ZengGalenos YayincilikNamık Kemal Tıp Dergisi2587-02622021-08-019210110710.4274/nkmj.galenos.2021.4685513049054Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor CandidatesBedriye KOYUNCU SÖKMEN0Tolga ŞAHİN1Alihan ORAL2Erdem KOÇAK3 Demiroğlu Bilim Üniversitesi, Gayrettepe Florence Nightingale Hastanesi, Radyoloji Kliniği, İstanbul, Türkiye Gayrettepe Florence Nightingale Hastanesi, Gastroenteroloji Kliniği, İstanbul, Türkiye Fenerbahçe Üniversitesi, Medicana Bahçelievler Hastanesi, İç Hastalıkları Kliniği, İstanbul, Türkiye Kadıköy Florence Nightingale Hastanesi, Gastroenteroloji Kliniği, İstanbul, Türkiye Aim:The presence of hepatosteatosis (HS) in the donor has negative effects on the results of liver transplantation (LT). Therefore, the detection of donor HS is vital during the pre-transplant period. The aim of this study was to compare the efficacy of liver biopsy and radiological methods in the detection of HS in live liver donor candidates.Materials and Methods:Two hundred twenty-six healthy individuals who were admitted to Demiroğlu Bilim University as donor candidates for LT were included in the study. Demographic, histopathological, laboratory and imaging findings of the donors were retrospectively reviewed. Computed tomography (CT) and magnetic resonance imaging (MRI) scans of the donors were retrospectively reevaluated and liver fat measurements were recorded.Results:39% (88) of the patients were female and 61% (138) were male. In the study population, the mean age was 34.3±8.7 years, the mean weight was 78.0±12.6 kg, the mean height was 169.1±9.6 cm, and the mean body mass index was 27.2±4.0. 42% of donors had <5% HS, and 58% of donors had >5% HS in liver biopsy. Both CT and MRI showed significant correlations with biopsy in HS detection (p<0.05).Conclusion:In our study, it was found that MRI correlated with biopsy as much as CT and could be used easily in the detection of HS. The use of MRI in liver donors may be more appropriate for donor health prior to transplantation. http://namikkemalmedj.com/archives/archive-detail/article-preview/comparison-of-biopsy-computed-tomography-and-magne/48565 liver transplantationdonor steatosishepatosteatozcomputed tomographymagnetic resonance imaging |
| spellingShingle | Bedriye KOYUNCU SÖKMEN Tolga ŞAHİN Alihan ORAL Erdem KOÇAK Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates Namık Kemal Tıp Dergisi liver transplantation donor steatosis hepatosteatoz computed tomography magnetic resonance imaging |
| title | Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates |
| title_full | Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates |
| title_fullStr | Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates |
| title_full_unstemmed | Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates |
| title_short | Comparison of Biopsy, Computed Tomography and Magnetic Resonance Imaging in the Detection of Hepatosteatosis in Live Liver Donor Candidates |
| title_sort | comparison of biopsy computed tomography and magnetic resonance imaging in the detection of hepatosteatosis in live liver donor candidates |
| topic | liver transplantation donor steatosis hepatosteatoz computed tomography magnetic resonance imaging |
| url |
http://namikkemalmedj.com/archives/archive-detail/article-preview/comparison-of-biopsy-computed-tomography-and-magne/48565
|
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