Effective Delivery of siRNA-Loaded Nanoparticles for Overcoming Oxaliplatin Resistance in Colorectal Cancer

Effective Delivery of siRNA-Loaded Nanoparticles for Overcoming Oxaliplatin Resistance in Colorectal Cancer

Chemotherapy resistance represents a formidable obstacle in advanced or metastatic colorectal cancer (CRC) patients. It is reported that ATPase copper transporting alpha (ATP7A) plays an important role in chemotherapy resistance in CRC. Here, we identified ATP7A as a potentially key gene of OXA resi...

Full description

Bibliographic Details
Main Authors: Yue Zhou, Qing Zhang, Minjia Wang, Chengzhi Huang, Xueqing Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
oxaliplatin
chemoresistance
siRNA delivery
colorectal cancer
ATP7A
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.827891/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.827891/full

Similar Items