Biologically-informed neural networks guide mechanistic modeling from sparse experimental data.
Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs are trained in a supervised learning framework to approxima...
Main Authors: | John H Lagergren, John T Nardini, Ruth E Baker, Matthew J Simpson, Kevin B Flores |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008462 |
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