Pregnancy outcomes in Korean women with ankylosing spondylitis
Background/Aims Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS. Methods Based on data from the Korean Health Insurance Review and Assessme...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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The Korean Association of Internal Medicine
2021-05-01
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| Series: | The Korean Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://www.kjim.org/upload/pdf/kjim-2019-144.pdf |
| _version_ | 1818916045060046848 |
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| author | Eun Hye Park Jung Sun Lee Ye-Jee Kim Seung Mi Lee Jong Kwan Jun Eun Bong Lee Yong-Gil Kim |
| author_facet | Eun Hye Park Jung Sun Lee Ye-Jee Kim Seung Mi Lee Jong Kwan Jun Eun Bong Lee Yong-Gil Kim |
| author_sort | Eun Hye Park |
| collection | DOAJ |
| description | Background/Aims Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS. Methods Based on data from the Korean Health Insurance Review and Assessment Service claims database since July 2007, maternal complications were compared between women with AS and 1:10 matched general population by maternal age and year of delivery. Additionally, the 27 deliveries from 21 patients with AS who were seen at a tertiary hospital were retrospectively evaluated using 1:4 matched control group by maternal and gestational age. Results In the population-based cohort, there were 1,293 deliveries in 996 patients with AS. Higher maternal age and more comorbidities were reported than in the general population. However, compared to age and delivery-year matched population, only the rate of Caesarean section (CS) was higher in women with AS (odds ratio, 1.52; 95% confidence interval, 1.36 to 1.70). Incidence of other maternal complications was comparable between women with AS and control subjects. In the hospital-based cohort, the CS rate was higher in women with AS (44.4% vs. 20.4%, p = 0.002). Causes of CS was not different in both groups, including previous uterine surgery. There were no significant differences in foetal outcomes, including growth restriction, foetal malformations and Apgar score. Conclusions CS deliveries were performed more often in women with AS. However, other maternal complications and offspring complications were similar between women with AS and healthy control subjects. |
| first_indexed | 2024-12-20T00:11:55Z |
| format | Article |
| id | doaj.art-c5338b1cb2944b7d8719218a8d879975 |
| institution | Directory Open Access Journal |
| issn | 1226-3303 2005-6648 |
| language | English |
| last_indexed | 2024-12-20T00:11:55Z |
| publishDate | 2021-05-01 |
| publisher | The Korean Association of Internal Medicine |
| record_format | Article |
| series | The Korean Journal of Internal Medicine |
| spelling | doaj.art-c5338b1cb2944b7d8719218a8d8799752022-12-21T20:00:29ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482021-05-0136372173010.3904/kjim.2019.144170240Pregnancy outcomes in Korean women with ankylosing spondylitisEun Hye Park0Jung Sun Lee1Ye-Jee Kim2Seung Mi Lee3Jong Kwan Jun4Eun Bong Lee5Yong-Gil Kim6 Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Division of Rheumatology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Division of Rheumatology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaBackground/Aims Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS. Methods Based on data from the Korean Health Insurance Review and Assessment Service claims database since July 2007, maternal complications were compared between women with AS and 1:10 matched general population by maternal age and year of delivery. Additionally, the 27 deliveries from 21 patients with AS who were seen at a tertiary hospital were retrospectively evaluated using 1:4 matched control group by maternal and gestational age. Results In the population-based cohort, there were 1,293 deliveries in 996 patients with AS. Higher maternal age and more comorbidities were reported than in the general population. However, compared to age and delivery-year matched population, only the rate of Caesarean section (CS) was higher in women with AS (odds ratio, 1.52; 95% confidence interval, 1.36 to 1.70). Incidence of other maternal complications was comparable between women with AS and control subjects. In the hospital-based cohort, the CS rate was higher in women with AS (44.4% vs. 20.4%, p = 0.002). Causes of CS was not different in both groups, including previous uterine surgery. There were no significant differences in foetal outcomes, including growth restriction, foetal malformations and Apgar score. Conclusions CS deliveries were performed more often in women with AS. However, other maternal complications and offspring complications were similar between women with AS and healthy control subjects.http://www.kjim.org/upload/pdf/kjim-2019-144.pdfspondylitis, ankylosingpregnancycaesarean section |
| spellingShingle | Eun Hye Park Jung Sun Lee Ye-Jee Kim Seung Mi Lee Jong Kwan Jun Eun Bong Lee Yong-Gil Kim Pregnancy outcomes in Korean women with ankylosing spondylitis The Korean Journal of Internal Medicine spondylitis, ankylosing pregnancy caesarean section |
| title | Pregnancy outcomes in Korean women with ankylosing spondylitis |
| title_full | Pregnancy outcomes in Korean women with ankylosing spondylitis |
| title_fullStr | Pregnancy outcomes in Korean women with ankylosing spondylitis |
| title_full_unstemmed | Pregnancy outcomes in Korean women with ankylosing spondylitis |
| title_short | Pregnancy outcomes in Korean women with ankylosing spondylitis |
| title_sort | pregnancy outcomes in korean women with ankylosing spondylitis |
| topic | spondylitis, ankylosing pregnancy caesarean section |
| url | http://www.kjim.org/upload/pdf/kjim-2019-144.pdf |
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