A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol
The purpose of this study was to compare patients who underwent on- vs. off-pump coronary artery bypass surgery managed with a fast-track protocol. Between September 2012 and December 2018, <i>n</i> = 3505 coronary artery bypass surgeries were managed with a fast-track protocol in our sp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/19/4470 |
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| author | Henrike Grützner Anna Flo Forner Massimiliano Meineri Aniruddha Janai Jörg Ender Waseem Zakaria Aziz Zakhary |
| author_facet | Henrike Grützner Anna Flo Forner Massimiliano Meineri Aniruddha Janai Jörg Ender Waseem Zakaria Aziz Zakhary |
| author_sort | Henrike Grützner |
| collection | DOAJ |
| description | The purpose of this study was to compare patients who underwent on- vs. off-pump coronary artery bypass surgery managed with a fast-track protocol. Between September 2012 and December 2018, <i>n</i> = 3505 coronary artery bypass surgeries were managed with a fast-track protocol in our specialized post-anesthesia care unit. Propensity score matching was applied and resulted in two equal groups of <i>n</i> = 926. There was no significant difference in ventilation time (on-pump 75 (55–120) min vs. off-pump 80 (55–120) min, <i>p</i> = 0.973). We found no statistically significant difference in primary fast-track failure in on-pump (8.2% (76)) vs. off-pump (6% (56)) groups (<i>p</i> = 0.702). The secondary fast-track failure rate was comparable (on-pump 12.9% (110) vs. off-pump 12.3% (107), <i>p</i> = 0.702). There were no significant differences between groups in regard to the post-anesthesia care unit, the intermediate care unit, and the hospital length of stay. Postoperative outcome and complications were also comparable, except for a statistically significant difference in PACU postoperative blood loss in on-pump (234 mL) vs. off-pump (323 mL, <i>p</i> < 0.0001) and red blood cell transfusion (11%) and (5%, <i>p</i> < 0.001), respectively. Our results suggest that on- and off-pump coronary artery bypass surgery in fast-track settings are comparable in terms of ventilation time, fast-track failure rate, and postoperative complications rate. |
| first_indexed | 2024-03-10T06:58:18Z |
| format | Article |
| id | doaj.art-c535ea3e0df84da1b6e1aeba1b093cb5 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:58:18Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-c535ea3e0df84da1b6e1aeba1b093cb52023-11-22T16:19:56ZengMDPI AGJournal of Clinical Medicine2077-03832021-09-011019447010.3390/jcm10194470A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track ProtocolHenrike Grützner0Anna Flo Forner1Massimiliano Meineri2Aniruddha Janai3Jörg Ender4Waseem Zakaria Aziz Zakhary5Section for Pediatrics and Youth Medicine, Public Health Department, Leipzig City Government, Friedrich-Ebert-Straße 19 a, 04109 Leipzig, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Heart Center Leipzig, Strümpellstraße 39, 04289 Leipzig, GermanyThe purpose of this study was to compare patients who underwent on- vs. off-pump coronary artery bypass surgery managed with a fast-track protocol. Between September 2012 and December 2018, <i>n</i> = 3505 coronary artery bypass surgeries were managed with a fast-track protocol in our specialized post-anesthesia care unit. Propensity score matching was applied and resulted in two equal groups of <i>n</i> = 926. There was no significant difference in ventilation time (on-pump 75 (55–120) min vs. off-pump 80 (55–120) min, <i>p</i> = 0.973). We found no statistically significant difference in primary fast-track failure in on-pump (8.2% (76)) vs. off-pump (6% (56)) groups (<i>p</i> = 0.702). The secondary fast-track failure rate was comparable (on-pump 12.9% (110) vs. off-pump 12.3% (107), <i>p</i> = 0.702). There were no significant differences between groups in regard to the post-anesthesia care unit, the intermediate care unit, and the hospital length of stay. Postoperative outcome and complications were also comparable, except for a statistically significant difference in PACU postoperative blood loss in on-pump (234 mL) vs. off-pump (323 mL, <i>p</i> < 0.0001) and red blood cell transfusion (11%) and (5%, <i>p</i> < 0.001), respectively. Our results suggest that on- and off-pump coronary artery bypass surgery in fast-track settings are comparable in terms of ventilation time, fast-track failure rate, and postoperative complications rate.https://www.mdpi.com/2077-0383/10/19/4470fast-track cardiac anesthesiarecovery areaon-pump coronary artery bypass surgeryoff-pump coronary artery bypass surgeryventilation time |
| spellingShingle | Henrike Grützner Anna Flo Forner Massimiliano Meineri Aniruddha Janai Jörg Ender Waseem Zakaria Aziz Zakhary A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol Journal of Clinical Medicine fast-track cardiac anesthesia recovery area on-pump coronary artery bypass surgery off-pump coronary artery bypass surgery ventilation time |
| title | A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol |
| title_full | A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol |
| title_fullStr | A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol |
| title_full_unstemmed | A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol |
| title_short | A Comparison of Patients Undergoing On- vs. Off-Pump Coronary Artery Bypass Surgery Managed with a Fast-Track Protocol |
| title_sort | comparison of patients undergoing on vs off pump coronary artery bypass surgery managed with a fast track protocol |
| topic | fast-track cardiac anesthesia recovery area on-pump coronary artery bypass surgery off-pump coronary artery bypass surgery ventilation time |
| url | https://www.mdpi.com/2077-0383/10/19/4470 |
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