Gliomatosis cerebri - A rare cause of bilateral blindness

We describe a rare case of gliomatosis cerebri (GC) with bilateral blindness. A 45-year-male presented with gradual painless loss of vision both eyes (BE), with generalised tonic–clonic seizures. On examination, the patient denied light perception BE, with sluggishly reacting pupil. Fundus examinati...

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Main Authors: Priyanka Sekar, P Rajarajeswary, Hannah Ranjee Prasanth, T S Ishwarya, Renuka Srinivasan, Ramesh Kannan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:TNOA Journal of Ophthalmic Science and Research
Subjects:
Online Access:http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=4;spage=304;epage=306;aulast=Sekar
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author Priyanka Sekar
P Rajarajeswary
Hannah Ranjee Prasanth
T S Ishwarya
Renuka Srinivasan
Ramesh Kannan
author_facet Priyanka Sekar
P Rajarajeswary
Hannah Ranjee Prasanth
T S Ishwarya
Renuka Srinivasan
Ramesh Kannan
author_sort Priyanka Sekar
collection DOAJ
description We describe a rare case of gliomatosis cerebri (GC) with bilateral blindness. A 45-year-male presented with gradual painless loss of vision both eyes (BE), with generalised tonic–clonic seizures. On examination, the patient denied light perception BE, with sluggishly reacting pupil. Fundus examination revealed papilledema and absent foveal reflex. Magnetic resonance imaging showed features of diffuse infiltrating glial tumor suggesting GC. Visual impairment can occur rarely due to optic nerve involvement, however bilateral cases has not been reported. Early recognition of GC may allow preservation of vision through focal radiotherapy to the optic nerve.
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spelling doaj.art-c5375ee34f48491b8e2359b29b79389c2022-12-21T19:44:42ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362020-01-0158430430610.4103/tjosr.tjosr_76_20Gliomatosis cerebri - A rare cause of bilateral blindnessPriyanka SekarP RajarajeswaryHannah Ranjee PrasanthT S IshwaryaRenuka SrinivasanRamesh KannanWe describe a rare case of gliomatosis cerebri (GC) with bilateral blindness. A 45-year-male presented with gradual painless loss of vision both eyes (BE), with generalised tonic–clonic seizures. On examination, the patient denied light perception BE, with sluggishly reacting pupil. Fundus examination revealed papilledema and absent foveal reflex. Magnetic resonance imaging showed features of diffuse infiltrating glial tumor suggesting GC. Visual impairment can occur rarely due to optic nerve involvement, however bilateral cases has not been reported. Early recognition of GC may allow preservation of vision through focal radiotherapy to the optic nerve.http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=4;spage=304;epage=306;aulast=Sekarglioblastomagliomatosis cerebrineuroimagingradiotherapy
spellingShingle Priyanka Sekar
P Rajarajeswary
Hannah Ranjee Prasanth
T S Ishwarya
Renuka Srinivasan
Ramesh Kannan
Gliomatosis cerebri - A rare cause of bilateral blindness
TNOA Journal of Ophthalmic Science and Research
glioblastoma
gliomatosis cerebri
neuroimaging
radiotherapy
title Gliomatosis cerebri - A rare cause of bilateral blindness
title_full Gliomatosis cerebri - A rare cause of bilateral blindness
title_fullStr Gliomatosis cerebri - A rare cause of bilateral blindness
title_full_unstemmed Gliomatosis cerebri - A rare cause of bilateral blindness
title_short Gliomatosis cerebri - A rare cause of bilateral blindness
title_sort gliomatosis cerebri a rare cause of bilateral blindness
topic glioblastoma
gliomatosis cerebri
neuroimaging
radiotherapy
url http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2020;volume=58;issue=4;spage=304;epage=306;aulast=Sekar
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AT prajarajeswary gliomatosiscerebriararecauseofbilateralblindness
AT hannahranjeeprasanth gliomatosiscerebriararecauseofbilateralblindness
AT tsishwarya gliomatosiscerebriararecauseofbilateralblindness
AT renukasrinivasan gliomatosiscerebriararecauseofbilateralblindness
AT rameshkannan gliomatosiscerebriararecauseofbilateralblindness