Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression

Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression

Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress. Echinochrome A (Ech A), a natural pigment isolated from sea urchins, exerts antioxidant and...

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Bibliographic Details
Main Authors: Hyeong Rok Yun, Sang Woo Ahn, Bomin Seol, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han, Kyung Soo Ko, Byoung Doo Rhee, Jung Eun Seol, Hyoung Kyu Kim
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Marine Drugs
Subjects:
atopic dermatitis
echinochrome A
NC/Nga mice
proinflammation
mast cell infiltration
Online Access:https://www.mdpi.com/1660-3397/19/11/622

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