The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations

Proton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae...

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Main Authors: N. Lalani, S. Alqarni, R. B. Jimenez
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/30/3/219
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author N. Lalani
S. Alqarni
R. B. Jimenez
author_facet N. Lalani
S. Alqarni
R. B. Jimenez
author_sort N. Lalani
collection DOAJ
description Proton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae for patients with locally advanced breast cancers. Thus, in the following review, we highlight clinical and technical considerations for proton radiotherapy delivery in patients with locally advanced breast cancer.
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spelling doaj.art-c5391d07f72d47c19672a9a12760294e2023-11-17T10:30:54ZengMDPI AGCurrent Oncology1198-00521718-77292023-02-013032869287810.3390/curroncol30030219The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical ConsiderationsN. Lalani0S. Alqarni1R. B. Jimenez2Department of Radiation Oncology, The Irving Greenberg Family Cancer Centre, Ottawa, ON K2H 8P4, CanadaDepartment of Radiation Oncology, The Irving Greenberg Family Cancer Centre, Ottawa, ON K2H 8P4, CanadaDepartment of Radiation Oncology, The Massachusetts General Hospital, Boston, MA 02114, USAProton therapy is a promising therapeutic modality with unique physical properties that allow for abrupt dose fall-off distal to the target of interest, thereby sparing nearby organs at risk. A number of studies have identified the utility of proton radiation in mitigating treatment related sequelae for patients with locally advanced breast cancers. Thus, in the following review, we highlight clinical and technical considerations for proton radiotherapy delivery in patients with locally advanced breast cancer.https://www.mdpi.com/1718-7729/30/3/219breast cancerproton therapyradiotherapy
spellingShingle N. Lalani
S. Alqarni
R. B. Jimenez
The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
Current Oncology
breast cancer
proton therapy
radiotherapy
title The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
title_full The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
title_fullStr The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
title_full_unstemmed The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
title_short The Potential of Proton Therapy for Locally Advanced Breast Cancer: Clinical and Technical Considerations
title_sort potential of proton therapy for locally advanced breast cancer clinical and technical considerations
topic breast cancer
proton therapy
radiotherapy
url https://www.mdpi.com/1718-7729/30/3/219
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